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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-PAX5 Polyclonal Antibody

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货号 TMAB-10013

Anti-PAX5 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PAX5。Anti-PAX5 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-PAX5 Polyclonal Antibody

Anti-PAX5 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-10013

Anti-PAX5 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PAX5。Anti-PAX5 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-PAX5 Polyclonal Antibody is a Rabbit antibody targeting PAX5. Anti-PAX5 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Chicken,Pig,Cow)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:200-800
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
组织特异性Expressed at early B-cell differentiation, in the developing CNS and in adult testis.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. Paired box transcription factors are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. This gene encodes the B-cell lineage specific activator protein that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis. This gene is located at 9p13, which is involved in t(9;14)(p13;q32) translocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas. This translocation brings the potent E-mu enhancer of the IgH gene into close proximity of the PAX5 promoter, suggesting that the deregulation of transcription of this gene contributes to the pathogenesis of these lymphomas. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]
抗原信息
免疫原
KLH conjugated synthetic peptide: human PAX5
抗原种属
Human
基因名称
PAX5
基因ID
5079
蛋白名称
Paired box protein Pax-5
Uniprot ID
Q02548
功能
May play an important role in B-cell differentiation as well as neural development and spermatogenesis. Involved in the regulation of the CD19 gene, a B-lymphoid-specific target gene.
化学信息
分子量Theoretical: 42 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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