MKK6 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 37.6 kDa and the accession number is A8K3Y2.
生物活性 | Kinase activity untested |
产品描述 | MKK6 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 37.6 kDa and the accession number is A8K3Y2. |
种属 | Human |
表达系统 | Baculovirus Insect Cells |
标签 | Tag Free |
蛋白编号 | A8K3Y2 |
别名 | MKK6, MAPKK6, SAPKK-3, SAPKK3, PRKMK6, MEK6, mitogen-activated protein kinase kinase 6 |
蛋白构建 | The Human MKK6 (NP_002749.2) (Met 1-Asp334) was expressed and purified with two additional amino acids (Gly & Pro ) at the N-terminus. |
蛋白纯度 | > 90 % as determined by SDS-PAGE |
分子量 | 37.6 kDa (predicted) |
内毒素 | < 1.0 EU/μg of the protein as determined by the LAL method. |
缓冲液 | Supplied as sterile 20 mM Tris, 500 mM NaCl, 3 mM DTT, 10% glycerol, pH 8.0. |
复溶方法 | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
存储 |
It is recommended to store the product under sterile conditions at -20℃ to -80℃. Samples are stable for up to 12 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 |
Kinases are highly recommended to be shipped at frozen temperature with blue ice or dry ice. |
研究背景 | Dual specificity mitogen-activated protein kinase kinase 6, also known as MAP kinase kinase 6, MAPKK 6, MAPK / ERK kinase 6, SAPKK3, MAP2K6, and MKK6, is a protein that belongs to the protein kinase superfamily, STE Ser / Thr protein kinase family and MAP kinase kinase subfamily. MAP2K6 / MKK6 contains one protein kinase domain. Mitogen-activated protein kinases are members of a conserved cascade of kinases involved in many signal transduction pathways. They stimulate phosphorylation of transcription factors in response to extracellular signals such as growth factors, cytokines, ultraviolet light, and stress-inducing agents. MAP2K6 / MKK6 exists in a variety of alternatively spliced isoforms with distinct patterns of tissue expression. Isoform 2 of MAP2K6 / MKK6 is only expressed in skeletal muscle. Isoform 1 of MAP2K6 / MKK6 is expressed in skeletal muscle, heart, and to a lesser extent in liver or pancreas. |
bottom
您可能有的问题的答案可以在重组蛋白操作手册中找到
MKK6 Protein, Human, Recombinant PRKMK 6 MAPKK-6 MKK6 MEK 6 MAPKK6 SAPKK-3 SAPKK3 PRKMK6 PRKMK-6 MAPKK 6 MEK6 SAPKK 3 MKK-6 MKK 6 mitogen-activated protein kinase kinase 6 MEK-6 recombinant recombinant-proteins proteins protein