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Anti-ISG15 Antibody-Biotin (8I780)

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Anti-ISG15 Antibody-Biotin (8I780)
产品编号 TMAY-02414B
别名 UCRP, ISG15 ubiquitin-like modifier, IP17, IMD38, IFI15, hUCRP, G1P2

Anti-ISG15 Antibody-Biotin (8I780) 是一种 Biotin-conjugated Rabbit 抗体,靶向 ISG15。Anti-ISG15 Antibody-Biotin (8I780) 可用于 ELISA。

Anti-ISG15 Antibody-Biotin (8I780)
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Anti-ISG15 Antibody-Biotin (8I780)

Rating icon 还可以
Anti-ISG15 Antibody-Biotin (8I780)
产品编号 TMAY-02414B 别名 UCRP, ISG15 ubiquitin-like modifier, IP17, IMD38, IFI15, hUCRP, G1P2

Anti-ISG15 Antibody-Biotin (8I780) 是一种 Biotin-conjugated Rabbit 抗体,靶向 ISG15。Anti-ISG15 Antibody-Biotin (8I780) 可用于 ELISA。

规格价格库存数量
100 μg
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-ISG15 Antibody-Biotin (8I780) is a Biotin-conjugated Rabbit antibody targeting ISG15. Anti-ISG15 Antibody-Biotin (8I780) can be used in ELISA.
别名UCRP, ISG15 ubiquitin-like modifier, IP17, IMD38, IFI15, hUCRP, G1P2
Ig Type
Rabbit IgG
克隆号
8I780
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 0.1-1 μg/mL
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human ISG15 (rh ISG15; TMPY-02348; AAH09507.1; Met1-Ser165) and then biotinylated..
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Interferon-induced 17 kDa protein (ISG15), a 15-kDa protein of unique primary amino acid sequence, functions intracellularly as a ubiquitin homolog and a cytokine that induces production of IFN-gamma and augments NK / lymphokine-activated killer cell proliferation and function. ISG15 is secreted from monocytes and lymphocytes. ISG15 is a ubiquitin-like molecule that is strongly upregulated by type I interferons as a primary response to diverse microbial and cellular stress stimuli. Alterations in the ISG15 signaling pathway have also been found in several human tumor entities. In addition to being stimulated by type I interferon, expression of ISG15 is greatly induced by viral or bacterial infection through the Janus kinase/signal transducer and activator of transcription (Jak / STAT) signaling pathway. After induction, ISG15 is secreted by monocytes, B- and T-lymphocytes, and fibroblasts. We demonstrate the novel way in which the function of the ISG15 protein is inhibited by influenza B virus, which strongly induces the ISG15 protein: a specific region of the influenza B virus NS1 protein, which includes part of its effector domain, blocks the covalent linkage of ISG15 to its target proteins both in vitro and in infected cells.
偶联与修饰
偶联
Biotin
其他可选修饰符
Unconjugated
可提供抗体种类
2
抗原信息
免疫原
Recombinant Protein: Human ISG15 protein (TMPY-02348)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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