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Interferon alpha 2/IFNA2 Protein, Rhesus, Recombinant (mFc)

产品编号 TMPY-03319

别名: interferon, alpha 2, interferon, α2, 干扰素, Interferon α2/IFNA2

Interferon alpha 2/IFNA2 Protein, Rhesus, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 45.9 kDa and the accession number is B6CK11.

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Interferon alpha 2/IFNA2 Protein, Rhesus, Recombinant (mFc)

规格	价格/CNY		货期	数量
100 μg	￥ 3,430		5日内发货

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参考文献

生物活性	Measured in antiviral assay using WISH human amnion cells infected with vesicular stomatitisvirus (VSV). The ED50 for this effect is typically 0.1-1 ng/mL.
产品描述	Interferon alpha 2/IFNA2 Protein, Rhesus, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 45.9 kDa and the accession number is B6CK11.

种属	Rhesus
表达系统	HEK293 Cells
标签	C-mFc
蛋白编号	B6CK11
别名	interferon, alpha 2, interferon, α2, 干扰素, Interferon α2/IFNA2
蛋白构建	The rhesus IFNA2 (NP_001129266.1) (Met1-Glu188) was expressed with Fc region of Mouse IgG1 at the C-terminus.
蛋白纯度	> 95 % as determined by SDS-PAGE
分子量	45.9 kDa (predicted)

内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	IFNA2 (Interferon Alpha 2) is a Protein Coding gene. This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Type I Interferons (IFNs) are well-known cytokines that exert antiviral activity, antitumor activity, and immunomodulatory effects. Interferon tau (IFNT), a type I IFN similar to alpha IFNs (IFNA), is the pregnancy recognition signal produced by the ruminant conceptus. Among the IFN-α genes, a total of 28 different sequence variants have been described. The three principal subtypes of IFNα-2 are designated α-2a, α-2b, and α-2c. IFNα-2b is being the predominant allele while IFNα-2a is less predominant and IFNα-2c only a minor allelic variant.

参考文献

1. Wang,et al.(2004) Fever of recombinant human interferon-alpha is mediated by opioid domain interaction with opioid receptor inducing prostaglandin E2. J Neuroimmunol. 156(1-2): 107-12. 2. Groopman JE,et al.(1984) Recombinant alpha-2 interferon therapy for Kaposi's sarcoma associated with the acquired immunodeficiency syndrome. Ann Intern Med. 100(5): 671-6. 3. Krueger JM,et al.(1987) Interferon alpha-2 enhances slow-wave sleep in rabbits. Int J Immunopharmacol. 9(1): 23-30.

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Keywords

Interferon alpha 2/IFNA2 Protein, Rhesus, Recombinant (mFc) interferon, alpha 2 interferon, α2 interferon, α 2 干扰素 Interferon α2/IFNA2 interferon, a 2 recombinant recombinant-proteins proteins protein

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