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顶部生物活性储存和溶解信息计算器

Anti-Frizzled-8 Antibody (5A651)

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产品编号 TMAC-01564

别名 hFZ8, FZD8, FZ-8, Frizzled-8, Frizzled8, frizzled family receptor 8, frizzled 8

Anti-Frizzled-8 Antibody (5A651) 是一种 Rabbit 抗体，靶向 Frizzled-8。Anti-Frizzled-8 Antibody (5A651) 可用于 IHC,WB。

Anti-Frizzled-8 Antibody (5A651)

Anti-Frizzled-8 Antibody (5A651)

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Rating icon 还可以
产品编号 TMAC-01564 别名 hFZ8, FZD8, FZ-8, Frizzled-8, Frizzled8, frizzled family receptor 8, frizzled 8

Anti-Frizzled-8 Antibody (5A651) 是一种 Rabbit 抗体，靶向 Frizzled-8。Anti-Frizzled-8 Antibody (5A651) 可用于 IHC,WB。

规格价格库存数量
50 μL
¥ 1,490
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-Frizzled-8 Antibody (5A651) is a Rabbit antibody targeting Frizzled-8. Anti-Frizzled-8 Antibody (5A651) can be used in IHC,WB.
别名hFZ8, FZD8, FZ-8, Frizzled-8, Frizzled8, frizzled family receptor 8, frizzled 8
Ig Type
IgG
克隆号
5A651
交叉反应
Human,Mouse
验证活性
1. Western blot analysis of Frizzled 8 on mouse lung tissue lysates using anti-Frizzled 8 antibody at 1/500 dilution.
2. Immunohistochemical analysis of paraffin-embedded human uterus tissue using anti-Frizzled 8 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-Frizzled 8 antibody. Counter stained with hematoxylin.
verifiedActivityverifiedActivityverifiedActivity
应用IHCWB
推荐剂量
WB: 1:500-1000; IHC: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Receptor for Wnt proteins. Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalosomes. The beta-catenin canonical signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Coreceptor along with RYK of Wnt proteins, such as WNT1.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
Q9H461
化学信息
分子量Theoretical: 73 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

FZD-8FZD 8FZ8FZ 8

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4个月前
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