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Anti-Frizzled-8 Antibody (5A651)
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产品编号 TMAC-01564
别名 hFZ8, FZD8, FZ-8, Frizzled-8, Frizzled8, frizzled family receptor 8, frizzled 8
Anti-Frizzled-8 Antibody (5A651) 是一种 Rabbit 抗体，靶向 Frizzled-8。Anti-Frizzled-8 Antibody (5A651) 可用于 WB,IHC。
Anti-Frizzled-8 Antibody (5A651)
Anti-Frizzled-8 Antibody (5A651)
还可以产品编号 TMAC-01564 别名 hFZ8, FZD8, FZ-8, Frizzled-8, Frizzled8, frizzled family receptor 8, frizzled 8
Anti-Frizzled-8 Antibody (5A651) 是一种 Rabbit 抗体，靶向 Frizzled-8。Anti-Frizzled-8 Antibody (5A651) 可用于 WB,IHC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,490 | 5日内发货 | |
| 100 μL | ¥ 2,490 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
化学信息
| 产品描述 | Anti-Frizzled-8 Antibody (5A651) is a Rabbit antibody targeting Frizzled-8. Anti-Frizzled-8 Antibody (5A651) can be used in WB,IHC. |
| 别名 | hFZ8, FZD8, FZ-8, Frizzled-8, Frizzled8, frizzled family receptor 8, frizzled 8 |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse |
| 验证活性 | 1. Western blot analysis of Frizzled 8 on mouse lung tissue lysates using anti-Frizzled 8 antibody at 1/500 dilution. 2. Immunohistochemical analysis of paraffin-embedded human uterus tissue using anti-Frizzled 8 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-Frizzled 8 antibody. Counter stained with hematoxylin. |
| 应用 | |
| 推荐剂量 | WB: 1:500-1000; IHC: 1:50-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | Receptor for Wnt proteins. Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalosomes. The beta-catenin canonical signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Coreceptor along with RYK of Wnt proteins, such as WNT1. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 73 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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