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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-ALKBH5 Polyclonal Antibody

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货号 TMAB-00096

别名 RNA demethylase ALKBH5, OFOXD1, Alpha-ketoglutarate-dependent dioxygenase alkB homolog 5, Alkylated DNA repair protein alkB homolog 5, ALKBH5, ABH5

Anti-ALKBH5 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ALKBH5。Anti-ALKBH5 Polyclonal Antibody 可用于 WB。

Anti-ALKBH5 Polyclonal Antibody

Anti-ALKBH5 Polyclonal Antibody

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货号 TMAB-00096 别名 RNA demethylase ALKBH5, OFOXD1, Alpha-ketoglutarate-dependent dioxygenase alkB homolog 5, Alkylated DNA repair protein alkB homolog 5, ALKBH5, ABH5

Anti-ALKBH5 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ALKBH5。Anti-ALKBH5 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-ALKBH5 Polyclonal Antibody is a Rabbit antibody targeting ALKBH5. Anti-ALKBH5 Polyclonal Antibody can be used in WB.
别名RNA demethylase ALKBH5, OFOXD1, Alpha-ketoglutarate-dependent dioxygenase alkB homolog 5, Alkylated DNA repair protein alkB homolog 5, ALKBH5, ABH5
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Dog,Cow,Rabbit)
验证活性
Sample:
Testis (Rat) Lysate at 40 μg
Lung (Mouse) Lysate at 40 μg
Primary: Anti-ALKBH5 (TMAB-00096) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 35-44 kDa
Observed band size: 40 kDa
verifiedActivity
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus speckle
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N(6)-methyladenosine (m6A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes. Requires molecular oxygen, alpha-ketoglutarate and iron. Demethylation of m6A mRNA affects mRNA processing and export and is required for spermatogenesis.
抗原信息
免疫原
KLH conjugated synthetic peptide: human ALKBH5
抗原种属
Human
基因名称
ALKBH5
基因ID
54890
蛋白名称
RNA demethylase ALKBH5
Uniprot ID
Q6P6C2
研究领域
DNA Damage Response
功能
Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N(6)-methyladenosine (m6A)RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes (PubMed:23177736, PubMed:24778178,PubMed:24616105, PubMed:24489119). Can also demethylate N(6)-methyladenosine in single-stranded DNA (in vitro)(PubMed:24616105). Requires molecular oxygen, alpha-ketoglutarate and iron (PubMed:21264265, PubMed:23177736, PubMed:24778178,PubMed:24616105, PubMed:24489119). Demethylation of m6A mRNA affects mRNA processing and export (PubMed:23177736). Required for spermatogenesis (By similarity).
化学信息
分子量Theoretical: 44 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | store at -20°C

计算器

  • 稀释 计算器

关键词

α-ketoglutarate-dependent dioxygenase alkB homolog 5OFOXD 1ALKBH 5a-ketoglutarate-dependent dioxygenase alkB homolog 5ABH 5
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