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Anti-Phospho-PTPN11 (Tyr580) Polyclonal Antibody 3
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还可以产品编号 TMAB-11196
Anti-Phospho-PTPN11 (Tyr580) Polyclonal Antibody 3 是一种 Rabbit 抗体，靶向 Phospho-PTPN11 (Tyr580)。Anti-Phospho-PTPN11 (Tyr580) Polyclonal Antibody 3 可用于 WB,IHC-P,IHC-Fr,IF,FCM。
Anti-Phospho-PTPN11 (Tyr580) Polyclonal Antibody 3
Anti-Phospho-PTPN11 (Tyr580) Polyclonal Antibody 3
一键复制产品信息 还可以产品编号 TMAB-11196
Anti-Phospho-PTPN11 (Tyr580) Polyclonal Antibody 3 是一种 Rabbit 抗体，靶向 Phospho-PTPN11 (Tyr580)。Anti-Phospho-PTPN11 (Tyr580) Polyclonal Antibody 3 可用于 WB,IHC-P,IHC-Fr,IF,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,165 | 5日内发货 | |
| 100 μL | ¥ 1,975 | 5日内发货 | |
| 200 μL | ¥ 2,790 | 5日内发货 |
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| 产品描述 | Anti-Phospho-PTPN11 (Tyr580) Polyclonal Antibody 3 is a Rabbit antibody targeting Phospho-PTPN11 (Tyr580). Anti-Phospho-PTPN11 (Tyr580) Polyclonal Antibody 3 can be used in WB,IHC-P,IHC-Fr,IF,FCM. |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse,Rat (predicted:Chicken,Horse) |
| 应用 | WBIHC-PIHC-FrIFFCM |
| 推荐剂量 | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 2μg/Test |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm. |
| 组织特异性 | Widely expressed, with highest levels in heart, brain, and skeletal muscle. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | The steady state of protein tyrosyl phosphorylation in cells is regulated by the opposing action of tyrosine kinases and protein tyrosine phosphatases (PTPs). Several groups have independently identified a non transmembrane PTP, designated SHPTP1 (also known as PTP1C, HCP and SHP), which is primarily expressed in hematopoietic cells and characterized by the presence of two SH2 domains N terminal to the PTP domain. A second and much more widely expressed PTP with SH2 domains, SHPTP2 (also designated PTP1D and Syp), has been identified. SHP2 is a protein tyrosine phosphatase that is widely expressed and plays a regulatory role in various cell |
| 免疫原 | KLH conjugated Synthesised phosphopeptide: human PTPN11/SHP2 around the phosphorylation site of Tyr580 |
| 抗原种属 | Human |
| 基因名称 | PTPN11 |
| 基因ID | |
| 蛋白名称 | Tyrosine-protein phosphatase non-receptor type 11 |
| Uniprot ID | |
| 功能 | Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity. |
| 分子量 | Theoretical: 66 kDa. |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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