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Anti-CST6 Antibody (6K349) 是一种 Mouse 抗体,靶向 CST6。Anti-CST6 Antibody (6K349) 可用于 ELISA,ELISA(Det)。
Anti-CST6 Antibody (6K349) 是一种 Mouse 抗体,靶向 CST6。Anti-CST6 Antibody (6K349) 可用于 ELISA,ELISA(Det)。
产品描述 | Anti-CST6 Antibody (6K349) is a Mouse antibody targeting CST6. Anti-CST6 Antibody (6K349) can be used in ELISA,ELISA(Det). |
Ig Type | Monoclonal Mouse IgG2a |
克隆号 | 6K349 |
交叉反应 | Human |
应用 | ELISA,ELISA(Det) |
推荐剂量 | ELISA: 1:1000-1:2000; ELISA(Det): 1:1000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Cystatin-M / CST6 (rh Cystatin-M; TMPY-00768; NP_001314.1; Met 1-Met 149). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Cystatin E/M, also referred to as CST6, is a member of type 2 cysteine proteinase inhibitors of the cystatin superfamily, and inhibits papain and cathepsin B. Cystatin E is a low molecular mass secreted protein existing in both a glycosylated (17 kDa) and an unglycosylated (14 kDa) form, with two characteristic intrachain disulfide bridges. Expression of cystatin M/E is found to be restricted to the epidermis, more specifically in the stratum granulosum, sweat glands, sebaceous glands, and the hair follicles. In addition to its function as a cysteine protease inhibitor, cystatin M/E also serves as a target for cross-linking by transglutaminases. Accordingly, cystatin M/E was suggested to be involved in barrier formation and maintenance. Furthermore, studies have revealed that cystatin M/E is frequently epigenetically inactivated during breast carcinogenesis, and thus be regarded as a candidate of tumour suppressor gene. |
偶联 | Unconjugated |
其他可选修饰符 | HRP |
可提供抗体种类 | 2 |
免疫原 | Recombinant Human CST6 protein (TMPY-00768) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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