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S100A9 Protein, Human, Recombinant

产品编号 TMPY-01330

别名: CAGB, MIF, 60B8AG, S100 calcium binding protein A9, CGLB, L1AG, NIF, MAC387, LIAG, MRP-14, P14, MRP14, CFAG

S100A9 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 26 and 13 kDa and the accession number is P06702.

TargetMol的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

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S100A9 Protein, Human, Recombinant

规格	价格/CNY		货期	数量
100 μg	￥ 4,460		5日内发货
1 mg	￥ 29,100		5日内发货

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参考文献

生物活性	This product displays no activity in cell-based assay.
产品描述	S100A9 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 26 and 13 kDa and the accession number is P06702.

种属	Human
表达系统	E. coli
标签	Tag Free
蛋白编号	P06702
别名	CAGB, MIF, 60B8AG, S100 calcium binding protein A9, CGLB, L1AG, NIF, MAC387, LIAG, MRP-14, P14, MRP14, CFAG
蛋白构建	native form of Human S100A9 (NP_002956.1) (Met 1-Pro 114)
蛋白纯度	> 95 % as determined by SDS-PAGE
分子量	26 & 13 kDa (predicted)

内毒素	Please contact us for more information.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that the protein is 100% soluble in ammonium sulfate at neutral pH. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from the neural crest, chondrocytes, macrophages, dendritic cells, etc. S100 proteins have been implicated in a variety of intracellular and extracellular functions. They are involved in regulation of protein phosphorylation, transcription factors, the dynamics of cytoskeleton constituents, enzyme activities, cell growth and differentiation, and the inflammatory response. Protein S100-A9, also known as S100 calciumbinding protein A9, S100A9, and CAGB, is a member of the S-100 family. S100A9 is expressed by macrophages in acutely inflammed tissues and in chronic inflammation. It is also expressed in epithelial cells constitutively or induced during dermatoses. S100A9 is a calcium-binding protein. It has anti-microbial activity towards bacteria and fungi. The anti-microbial and proapoptotic activity of S100A9 is inhibited by zinc ions. S100A9 plays a role in the development of endotoxic shock in response to bacterial lipopolysaccharide (LPS). It promotes tubulin polymerization when unphosphorylated. It also promotes phagocyte migration and infiltration of granulocytes at sites of wounding. S100A9 plays a role as a proinflammatory mediator in acute and chronic inflammation and up-regulates the release of IL8 and cell-surface expression of ICAM1.

参考文献

1. Miyasaki KT. et al., 1993, J Dent Res. 72: 517-23. 2. Fanò G. et al., 1995, Prog Neurobiol. 46 (1): 71-82. 3. Vogl T. et al., 2004, Blood. 104: 4260-8. 4. Viemann D. et al., 2005, Blood. 105: 2955-62. 5. Nakatani Y. et al., 2005, Mediators Inflamm. 2005: 280-92. 6. Bjoerk P. et al., 2009, PLoS Biol. 7: E97-E97.

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Keywords

S100A9 Protein, Human, Recombinant CAGB MAC-387 MIF 60B8AG S100 calcium binding protein A9 CGLB L1AG MRP 14 P 14 NIF MAC387 LIAG MAC 387 MRP-14 P14 MRP14 P-14 CFAG recombinant recombinant-proteins proteins protein

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