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顶部产品介绍偶联与修饰抗原信息化学信息储存和溶解信息计算器

Anti-NR1D1 Antibody (2D57)

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货号 TMAC-02888

别名 V-erbA-related protein 1, Thyroid hormone receptor, alpha-1- like, Thyroid hormone receptor, alpha like, THRAL, THRA1, Rev-erbA-alpha, Rev-ErbAalpha, Reverba, Rev erbalpha, Rev erbAalpha, Nuclear receptor subfamily 1 group D member 1, Nuclear receptor Rev ErbA alpha, NR1D1_HUMAN, Nr1d1, hRev, ERBA-related 1, EAR-1, EAR1

Anti-NR1D1 Antibody (2D57) 是一种 Rabbit 抗体，靶向 NR1D1。Anti-NR1D1 Antibody (2D57) 可用于 IHC,WB。

Anti-NR1D1 Antibody (2D57)

Anti-NR1D1 Antibody (2D57)

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货号 TMAC-02888 别名 V-erbA-related protein 1, Thyroid hormone receptor, alpha-1- like, Thyroid hormone receptor, alpha like, THRAL, THRA1, Rev-erbA-alpha, Rev-ErbAalpha, Reverba, Rev erbalpha, Rev erbAalpha, Nuclear receptor subfamily 1 group D member 1, Nuclear receptor Rev ErbA alpha, NR1D1_HUMAN, Nr1d1, hRev, ERBA-related 1, EAR-1, EAR1

Anti-NR1D1 Antibody (2D57) 是一种 Rabbit 抗体，靶向 NR1D1。Anti-NR1D1 Antibody (2D57) 可用于 IHC,WB。

规格价格库存数量
50 μL
¥ 1,490
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-NR1D1 Antibody (2D57) is a Rabbit antibody targeting NR1D1. Anti-NR1D1 Antibody (2D57) can be used in IHC,WB.
别名V-erbA-related protein 1, Thyroid hormone receptor, alpha-1- like, Thyroid hormone receptor, alpha like, THRAL, THRA1, Rev-erbA-alpha, Rev-ErbAalpha, Reverba, Rev erbalpha, Rev erbAalpha, Nuclear receptor subfamily 1 group D member 1, Nuclear receptor Rev ErbA alpha, NR1D1_HUMAN, Nr1d1, hRev, ERBA-related 1, EAR-1, EAR1
Ig Type
IgG
克隆号
2D57
反应种属
Human,Mouse
验证活性
1. Western blot analysis of NR1D1 on HepG2 and SiHa cell lysates using anti-NR1D1 antibody at 1/500 dilution.
2. Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-NR1D1 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human uterus tissue using anti-NR1D1 antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded mouse fallopian tubes using anti-NR1D1 antibody. Counter stained with hematoxylin.
verifiedActivityverifiedActivityverifiedActivityverifiedActivity
应用IHCWB
推荐剂量
WB: 1:500-1000; IHC: 1:100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Transcriptional repressor which coordinates circadian rhythm and metabolic pathways in a heme-dependent manner. Integral component of the complex transcription machinery that governs circadian rhythmicity and forms a critical negative limb of the circadian clock by directly repressing the expression of core clock components ARTNL/BMAL1, CLOCK and CRY1. Also regulates genes involved in metabolic functions, including lipid and bile acid metabolism, adipogenesis, gluconeogenesis and the macrophage inflammatory response. Acts as a receptor for heme which stimulates its interaction with the NCOR1/HDAC3 corepressor complex, enhancing transcriptional repression. Recognizes two classes of DNA response elements within the promoter of its target genes and can bind to DNA as either monomers or homodimers, depending on the nature of the response element. Binds as a monomer to a response element composed of the consensus half-site motif 5'-[A/G]GGTCA-3' preceded by an A/T-rich 5' sequence (RevRE), or as a homodimer to a direct repeat of the core motif spaced by two nucleotides (RevDR-2).
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
P20393
化学信息
分子量Theoretical: 67 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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