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Anti-Phospho-NFKBIA (Tyr305) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-NFKBIA (Tyr305)。Anti-Phospho-NFKBIA (Tyr305) Polyclonal Antibody 可用于 WB。
Anti-Phospho-NFKBIA (Tyr305) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-NFKBIA (Tyr305)。Anti-Phospho-NFKBIA (Tyr305) Polyclonal Antibody 可用于 WB。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,485 | 5日内发货 | |
100 μL | ¥ 2,240 | 5日内发货 |
产品描述 | Anti-Phospho-NFKBIA (Tyr305) Polyclonal Antibody is a Rabbit antibody targeting Phospho-NFKBIA (Tyr305). Anti-Phospho-NFKBIA (Tyr305) Polyclonal Antibody can be used in WB. |
别名 | p-NFKBIA (Y305), p-NFKBIA (Tyr305), NFKBIA (p-Y305), NFKBIA (p-Tyr305) |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat,Monkey |
验证活性 | 1. Western blot analysis of extracts from COS-7 cells using I kappaB- alpha (Phospho-Tyr305) Antibody TMAC-02078. The lane on the left is treated with the antigen-specific peptide. |
应用 | |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
性状 | Liquid |
缓冲液 | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
研究背景 | Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription. |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | Peptide sequence around phosphorylation site of Tyrosine 305(L-P-Y(p)-D-D) derived from Human I kappaB- alpha |
抗原种属 | human |
Uniprot ID |
分子量 | Actual: 39 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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