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Anti-Nm23-H2/NME2 Polyclonal Antibody

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货号 TMAB-09523

Anti-Nm23-H2/NME2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Nm23-H2/NME2。Anti-Nm23-H2/NME2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-Nm23-H2/NME2 Polyclonal Antibody

Anti-Nm23-H2/NME2 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-09523

Anti-Nm23-H2/NME2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Nm23-H2/NME2。Anti-Nm23-H2/NME2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-Nm23-H2/NME2 Polyclonal Antibody is a Rabbit antibody targeting Nm23-H2/NME2. Anti-Nm23-H2/NME2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus. Note=Isoform 2 is mainly cytoplasmic and isoform 1 and isoform 2 are excluded from the nucleolus.
组织特异性Ubiquitously expressed.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景NM23 is a heterodimeric protein functioning as a nucleoside diphosphate (NDP) kinase. NME1 and NME2 comprise the 152 amino acid A and B polypeptide chains of the NM23 enzyme, respectively. NME2 is identical to the beta subunit of human erythrocyte NDP kinase. NDP kinases are involved in the synthesis of nucleoside triphosphates, and NM23 may act in the regulation of signal transduction by complexing with G proteins, causing activation/inactivation of developmental pathways. NEM2 has been identified as a putative tumor suppressor. High expression of mouse NME2 is detected in heart, liver, and kidney, with moderate expression in skeletal muscle, and negligible expression in other mouse tissues examined.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Nm23
抗原种属
Human
基因名称
NME2
基因ID
4831
蛋白名称
Nucleoside diphosphate kinase B
Uniprot ID
P22392
功能
Major role in the synthesis of nucleoside triphosphates other than ATP. Negatively regulates Rho activity by interacting with AKAP13/LBC. Acts as a transcriptional activator of the MYC gene; binds DNA non-specifically (PubMed:8392752). Exhibits histidine protein kinase activity.
化学信息
分子量Theoretical: 17 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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