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顶部生物活性储存和溶解信息计算器

Anti-IL-6R Antibody-PE (5X839)

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Anti-IL-6R Antibody-PE (5X839)
产品编号 TMAY-03209P
别名 interleukin 6 receptor, IL6RQ, IL-6RA, IL6RA, IL-6R-1, IL-6R, IL6Q, gp80, CD126

Anti-IL-6R Antibody-PE (5X839) 是一种 PE-conjugated Rabbit 抗体，靶向 IL-6R。Anti-IL-6R Antibody-PE (5X839) 可用于 FCM。

Anti-IL-6R Antibody-PE (5X839)
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Anti-IL-6R Antibody-PE (5X839)

Rating icon 还可以
Anti-IL-6R Antibody-PE (5X839)
产品编号 TMAY-03209P 别名 interleukin 6 receptor, IL6RQ, IL-6RA, IL6RA, IL-6R-1, IL-6R, IL6Q, gp80, CD126

Anti-IL-6R Antibody-PE (5X839) 是一种 PE-conjugated Rabbit 抗体，靶向 IL-6R。Anti-IL-6R Antibody-PE (5X839) 可用于 FCM。

规格价格库存数量
25 T
¥ 680
5日内发货
100 T
¥ 2,185
5日内发货
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产品介绍

生物活性
产品描述
Anti-IL-6R Antibody-PE (5X839) is a PE-conjugated Rabbit antibody targeting IL-6R. Anti-IL-6R Antibody-PE (5X839) can be used in FCM.
别名interleukin 6 receptor, IL6RQ, IL-6RA, IL6RA, IL-6R-1, IL-6R, IL6Q, gp80, CD126
Ig Type
Rabbit IgG
克隆号
5X839
交叉反应
Mouse
验证活性
Flow cytometric analysis of Mouse IL-6R expression on BABL/c splenocytes. Cells were stained with PE-conjugated anti-Human Mouse IL-6R. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
应用
FCM
推荐剂量
10 μl/Test, 0.1 mg/ml
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Mouse IL-6R / CD126 (rM IL-6R / CD126; TMPY-01214; NP_034689.2; Ile44-Glu357) and conjugated with PE under optimum conditions, the unreacted PE was removed.
纯化方式Protein A
性状Liquid
缓冲液PBS solution containing 0.5% BSA and 0.09% sodium azide
研究背景Interleukin 6 receptor (IL-6R) also known as CD126 (Cluster of Differentiation 126) is a type I cytokine receptor. The low concentration of a soluble form of IL-6 receptor (SIL-6R) acts as an agonist of IL-6 activity. In the IL-6R/CD126/IL6R system, both a membrane-bound IL-6R and a SIL-6R protein can mediate IL-6 signals into the cells through the interaction of gp130. The resulting IL-6/sIL-6R protein complex is also capable of binding to gp130 and inducing intracellular signaling. Through this so-called 'trans-signaling' mechanism, IL-6 can stimulate cells that lack an endogenous mIL-6R. High levels of IL-6 and SIL-6R have been reported in several chronic inflammatory and autoimmune diseases as well as in cancer.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
偶联与修饰
偶联
PE
其他可选修饰符
Unconjugated/APC
可提供抗体种类
3
抗原信息
免疫原
Recombinant Protein: Mouse IL-6R / CD126 protein (TMPY-01214)
抗原种属
Mouse
研究领域
Neuroinflammation
存储&运输
储存方式Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
运输方式Shipping with blue ice.

计算器

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关键词

CD-126CD 126

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