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Anti-ITGAX Antibody (4P951) 是一种 Rabbit 抗体,靶向 ITGAX。Anti-ITGAX Antibody (4P951) 可用于 WB,IHC,IP,ICC/IF。
Anti-ITGAX Antibody (4P951) 是一种 Rabbit 抗体,靶向 ITGAX。Anti-ITGAX Antibody (4P951) 可用于 WB,IHC,IP,ICC/IF。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,480 | 5日内发货 | |
100 μL | ¥ 2,480 | 5日内发货 |
产品描述 | Anti-ITGAX Antibody (4P951) is a Rabbit antibody targeting ITGAX. Anti-ITGAX Antibody (4P951) can be used in WB,IHC,IP,ICC/IF. |
别名 | SLEB6, leukocyte adhesion receptor p150, 95, leukocyte adhesion glycoprotein p150, 95 alpha chain, ITGAX, ITAX, integrin aX, integrin alpha-X precursor, Integrin alpha-X, complement receptor 4, CD11C(p150) alpha polypeptide, CD11 antigen-like family member C |
Ig Type | IgG |
交叉反应 | Human |
验证活性 | 1. Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-CD11c antibody. Counter stained with hematoxylin. 2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CD11c antibody. Counter stained with hematoxylin. |
应用 | |
推荐剂量 | WB: 1:1000-2000; IHC: 1:50-200; ICC/IF: 1:50-200 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | Integrin αX (CD11C, leukocyte surface antigen p150,95, CR4, Axb2) is a type 1 transmembrane protein that traditionally combines with β2 chain to form a leukocyte-specific integrin known as inactivated-C3b (iC3b) receptor 4 (CR4). Integrin αX/β2 shares similar properties of the αM/β2 integrin in mediating adherence of neutrophils and monocytes to stimulated endothelial cells, and in phagocytosis of complement coated particles. Abnormal expression of Integrin αX is characteristic of hairy cell leukemia (HCL) and is dependent upon activation of proto-oncogenes Ras and JunD. Proteins and DNA elements that influence transcription of Integrin αX include Sp1 and Sp1-like factors, AP-1 family, C/EBP, Oct-2 and PU.1. Integrin αX is present on monocyte derivative dendritic cells (DCs), macrophages and NK cells. Upon activation, DCs present in skin (Langerhans cells), lining of nose, lung, stomach, intestine and blood can migrate to lymphoid tissues and interact with T and B cells to initiate and shape the immune response. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 128 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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