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Anti-Phospho-alpha Adducin (Ser436) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-alpha Adducin (Ser436)。Anti-Phospho-alpha Adducin (Ser436) Polyclonal Antibody 可用于 WB。
Anti-Phospho-alpha Adducin (Ser436) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-alpha Adducin (Ser436)。Anti-Phospho-alpha Adducin (Ser436) Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,170 | 5日内发货 | |
| 100 μL | ¥ 1,975 | 5日内发货 | |
| 200 μL | ¥ 2,785 | 5日内发货 |
| 产品描述 | Anti-Phospho-alpha Adducin (Ser436) Polyclonal Antibody is a Rabbit antibody targeting Phospho-alpha Adducin (Ser436). Anti-Phospho-alpha Adducin (Ser436) Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| 反应种属 | Human,Mouse (predicted:Rat,Chicken,Dog,Cow,Horse) |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side. |
| 组织特异性 | Expressed in all tissues. Found in much higher levels in reticulocytes than the beta subunit. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | Adducins are a family of cytoskeleton proteins encoded by three genes (Alpha, Beta, Gamma). Adducin is a protein associated with the inner leaflet of the plasma membrane and is one of the proteins localized at the spectrin-actin junction of the membrane skeleton. The cortical actin cytoskeletal network is lost during apoptosis and Adducins are central in the cortical actin network organization. Adducin Alpha is a cytoskeletal protein involved with sodium-pump activity in the renal tubule and is associated with hypertension. The expression of Adducin Alpha and Adducin Gamma is ubiquitous in contrast to the restricted expression of Adducin Beta. Adducin Beta is expressed at high levels in brain and hematopoietic tissues, such as bone marrow, in humans, and in spleen in mice. |
| 免疫原 | KLH conjugated synthesised phosphopeptide: human alpha Adducin around the phosphorylation site of Ser436 |
| 抗原种属 | Human |
| 基因名称 | ADD1 |
| 基因ID | |
| 蛋白名称 | alpha-adducin |
| Uniprot ID | |
| 功能 | Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to calmodulin. |
| 分子量 | Theoretical: 81 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |