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Anti-FABP4 Antibody (8Y254) 是一种 Rabbit 抗体,靶向 FABP4。Anti-FABP4 Antibody (8Y254) 可用于 ELISA。
Anti-FABP4 Antibody (8Y254) 是一种 Rabbit 抗体,靶向 FABP4。Anti-FABP4 Antibody (8Y254) 可用于 ELISA。
产品描述 | Anti-FABP4 Antibody (8Y254) is a Rabbit antibody targeting FABP4. Anti-FABP4 Antibody (8Y254) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 8Y254 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human FABP4 / ALBP / A-FABP (rh FABP4 / ALBP / A-FABP; TMPY-02103; P15090; Cys2-Ala132,29Ala/Thr). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Fatty acid-binding protein, adipocyte, also known as Adipocyte-type fatty acid-binding protein, Fatty acid-binding protein 4, Adipocyte lipid-binding protein, and FABP4, is a cytoplasm protein which belongs to thecalycin superfamily and Fatty-acid binding protein (FABP) family. In familial combined hyperlipidemia (FCHL), FABP4 correlated to body mass index (BMI), waist circumference and homeostasis model assessment (HOMA) index.FABP4 levels were associated with triglyceride-rich lipoproteins. In humans serum FABP4 levels correlate significantly with features of PCOS. It appears to be a determinant of atherogenic dyslipidemia. FABP4 pathway mediates the sebaceous gland hyperplasia in keratinocyte-specific Pten-null mice. FABP4 concentration significantly increased with an increasing of MS features and was strongly correlated with body-mass index, triglycerides, HDL-cholesterol concentrations and blood pressure. Patients in the highest quartile of FABP4 presented a six-fold increased odds ratio for MS and a three-fold increased odds for LD, adjusted by age, sex, body-mass index and the antiretroviral therapy. FABP4 is a strong plasma marker of metabolic disturbances in HIV-infected patients, and therefore, could serve to guide therapeutic intervention in this group of patients. |
偶联 | Unconjugated |
免疫原 | Recombinant Human FABP4 / ALBP / A-FABP Protein (TMPY-02103) |
抗原种属 | Human |
研究领域 | Early Mesodermal Lineage Markers |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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