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Anti-CHST1 Polyclonal Antibody

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货号 TMAB-04340

Anti-CHST1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CHST1。Anti-CHST1 Polyclonal Antibody 可用于 FCM。

Anti-CHST1 Polyclonal Antibody

Anti-CHST1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-04340

Anti-CHST1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CHST1。Anti-CHST1 Polyclonal Antibody 可用于 FCM。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-CHST1 Polyclonal Antibody is a Rabbit antibody targeting CHST1. Anti-CHST1 Polyclonal Antibody can be used in FCM.
Ig Type
IgG
反应种属
Rat (predicted:Rabbit,Horse,Cow,Pig,Dog,Chicken,Mouse,Human)
应用FCM
推荐剂量
FCM: 1μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Golgi apparatus membrane; Single-pass type II membrane protein.
组织特异性Widely expressed at low level. Expressed in brain and skeletal muscle. Expressed by high endothelial cells (HEVs) and leukocytes.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Catalyzes the transfer of sulfate to position 6 of galactose residues of keratan. It has a preference for sulfating keratan sulfate, but it also transfers sulfate to the unsulfated polymer. The sulfotransferase activity on sialyl LacNAc structures is much higher than the corresponding desialylated substrate, and only internal galactose residues are sulfated. It also may function in the sulfation of sialyl N-acetyllactosamine oligosaccharide chains attached to glycoproteins. It participates in biosynthesis of selectin ligands. Selectin ligands are present in high endothelial cells (HEVs) and play a central role in lymphocyte homing at sites of inflammation. Aggrecan is the major proteoglycan of human articular cartilage. The core protein is substituted by a number of keratan sulfate and chondroitin sulfate glycosaminoglycan chains. Whereas chondroitin sulfate is widely distributed throughout the body, keratan sulfate is primarily expressed in cartilage (joints, trachea, intervertebral discs) and cornea.
抗原信息
免疫原
KLH conjugated synthetic peptide: human CHST1
抗原种属
Human
基因名称
CHST1
基因ID
8534
蛋白名称
Carbohydrate sulfotransferase 1
Uniprot ID
O43916
功能
Catalyzes the transfer of sulfate to position 6 of galactose (Gal) residues of keratan. Has a preference for sulfating keratan sulfate, but it also transfers sulfate to the unsulfated polymer. The sulfotransferase activity on sialyl LacNAc structures is much higher than the corresponding desialylated substrate, and only internal Gal residues are sulfated. May function in the sulfation of sialyl N-acetyllactosamine oligosaccharide chains attached to glycoproteins. Participates in biosynthesis of selectin ligands. Selectin ligands are present in high endothelial cells (HEVs) and play a central role in lymphocyte homing at sites of inflammation.
化学信息
分子量Theoretical: 45 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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