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Anti-Matrin 3 Antibody (7P173)

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Anti-Matrin 3 Antibody (7P173)
产品编号 TMAC-02481
别名 Vocal cord and pharyngeal weakness with distal myopathy, VCPDM, MPD2, Matrin-3, Matrin3, MATR3_HUMAN, Matr3, KIAA0723, ALS21

Anti-Matrin 3 Antibody (7P173) 是一种 Rabbit 抗体,靶向 Matrin 3。Anti-Matrin 3 Antibody (7P173) 可用于 WB,ICC,IF,IHC,FCM。

Anti-Matrin 3 Antibody (7P173)

Anti-Matrin 3 Antibody (7P173)

Rating icon 还可以
Anti-Matrin 3 Antibody (7P173)
产品编号 TMAC-02481 别名 Vocal cord and pharyngeal weakness with distal myopathy, VCPDM, MPD2, Matrin-3, Matrin3, MATR3_HUMAN, Matr3, KIAA0723, ALS21

Anti-Matrin 3 Antibody (7P173) 是一种 Rabbit 抗体,靶向 Matrin 3。Anti-Matrin 3 Antibody (7P173) 可用于 WB,ICC,IF,IHC,FCM。

规格价格库存数量
50 μL
¥ 1,485
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-Matrin 3 Antibody (7P173) is a Rabbit antibody targeting Matrin 3. Anti-Matrin 3 Antibody (7P173) can be used in WB,ICC,IF,IHC,FCM.
别名Vocal cord and pharyngeal weakness with distal myopathy, VCPDM, MPD2, Matrin-3, Matrin3, MATR3_HUMAN, Matr3, KIAA0723, ALS21
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of Matrin 3 on different lysates using anti-Matrin 3 antibody at 1/1,000 dilution. Positive control: Lane 1: Daudi, Lane 2: Mouse brain tissue.
2. Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-Matrin 3 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Matrin 3 antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded human lung cancer tissue using anti-Matrin 3 antibody. Counter stained with hematoxylin.
5. Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-Matrin 3 antibody. Counter stained with hematoxylin.
6. Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-Matrin 3 antibody. Counter stained with hematoxylin.
7. ICC staining Matrin 3 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
8. ICC staining Matrin 3 in LOVO cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
9. ICC staining Matrin 3 in SH-SY-5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
10. Flow cytometric analysis of LOVO cells with Matrin 3 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.
应用
推荐剂量
WB: 1:1000-2000; IHC: 1:50-200; ICC: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Matrin-3 is a nuclear matrix protein containing one matrin-type zinc finger and two RRM (RNA recognition motif) domains. Matrin-3 plays a role in transcription and may interact with other nuclear matrix proteins to form the internal fibrogranular network. In association with the PSF-p54/NRB heteromer, Matrin-3 may play a role in the nuclear retention of defective RNAs. As the main substrate for PKA-mediated phosphorylation, Matrin-3 may serve as a rapid way of transferring information from synapses containing NMDA receptors to neuronal nuclei under physiological conditions. Also, the phosphorylation of Matrin-3 may contribute to neuronal death under pathological conditions. It is likely that Matrin-3 activity is regulated by calcium dependent interaction with CaM I and also by caspase induced cleavage.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
化学信息
分子量Theoretical: 95 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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