Powder: -20°C for 3 years | In solvent: -80°C for 1 year
FATP1-IN-1 是一种强效的脂肪酸转运蛋白1(FATP1)抑制剂。它能有效抑制对FATP1功能至关重要的重组人类或小鼠的酰辅酶A合成酶活性。其抑制特征通过IC50值体现,分别为人类FATP1的0.046 μM 和小鼠FATP1的0.60 μM。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
1 mg | ¥ 996 | 现货 | ||
5 mg | ¥ 2,450 | 现货 | ||
10 mg | ¥ 3,930 | 现货 | ||
25 mg | ¥ 6,290 | 现货 | ||
50 mg | ¥ 8,660 | 现货 | ||
100 mg | ¥ 11,600 | 现货 | ||
500 mg | ¥ 23,300 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 2,690 | 现货 |
产品描述 | FATP1-IN-1 is a potent inhibitor of fatty acid transport protein 1 (FATP1). It effectively inhibits the activity of recombinant human or mouse acyl-CoA synthetase, which is essential for the function of FATP1. The inhibition is characterized by IC50 values of 0.046 μM for human FATP1 and 0.60 μM for mouse FATP1. |
体内活性 | FATP1-IN-1 (p.o.; 10 mg/kg) treatment shows the C max , AUC and T max were 5.5 μg/mL, 36 μg h/mL and 0.33 hours, respectively, and exceeds the mouse IC 50 value of 0.22 μM without considering plasma protein binding. Animal Model: Mouse plasma [1] Dosage: 10 mg/kg Administration: P.o. Result: The C max , AUC and T max were 5.5 μg/mL, 36 μg h/mL and 0.33 hours, respectively. |
别名 | FATP1-IN-1 |
分子量 | 375.46 |
分子式 | C18H22FN5OS |
CAS No. | 1431945-95-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 56.2 mg/mL (149.8 mM), Sonication is recommended.
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 2.6634 mL | 13.317 mL | 26.634 mL | 66.585 mL |
5 mM | 0.5327 mL | 2.6634 mL | 5.3268 mL | 13.317 mL | |
10 mM | 0.2663 mL | 1.3317 mL | 2.6634 mL | 6.6585 mL | |
20 mM | 0.1332 mL | 0.6658 mL | 1.3317 mL | 3.3292 mL | |
50 mM | 0.0533 mL | 0.2663 mL | 0.5327 mL | 1.3317 mL | |
100 mM | 0.0266 mL | 0.1332 mL | 0.2663 mL | 0.6658 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
FATP1-IN-1 1431945-95-7 Others FATP1 IN 1 FATP1IN1 FATP-1-IN-1 Inhibitor inhibitor inhibit