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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Dnmt3a Antibody (4D866)

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货号 TMAB-05261

Anti-Dnmt3a Antibody (4D866) 是一种 Rabbit 抗体，靶向 Dnmt3a。Anti-Dnmt3a Antibody (4D866) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM。

Anti-Dnmt3a Antibody (4D866)

Anti-Dnmt3a Antibody (4D866)

一键复制产品信息
Rating icon 还可以
货号 TMAB-05261

Anti-Dnmt3a Antibody (4D866) 是一种 Rabbit 抗体，靶向 Dnmt3a。Anti-Dnmt3a Antibody (4D866) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM。

规格价格库存数量
25 μL
¥ 780
5日内发货
50 μL
¥ 1,390
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-Dnmt3a Antibody (4D866) is a Rabbit antibody targeting Dnmt3a. Anti-Dnmt3a Antibody (4D866) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM.
Ig Type
IgG
克隆号
4D866
反应种属
Human,Mouse,Rat
应用WBIHC-PIHC-FrICC/IFIFFCM
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:50-200; IF: 1:100-500; FCM: 1μg/Test
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Nucleus. Cytoplasm. Note=Accumulates in the major satellite repeats at pericentric heterochromatin.
组织特异性Highly expressed in fetal tissues, skeletal muscle, heart, peripheral blood mononuclear cells, kidney, and at lower levels in placenta, brain, liver, colon, spleen, small intestine and lung.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development.DNA methylation is coordinated with methylation of histones.
抗原信息
免疫原
A synthesized peptide: human DNMT3A
抗原种属
Human
基因名称
DNMT3A
基因ID
1788
蛋白名称
DNA(cytosine-5)-methyltransferase 3A
Uniprot ID
Q9Y6K1
功能
Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. It modifies DNA in a non-processive manner and also methylates non-CpG sites. May preferentially methylate DNA linker between 2 nucleosomal cores and is inhibited by histone H1. Plays a role in paternal and maternal imprinting. Required for methylation of most imprinted loci in germ cells. Acts as a transcriptional corepressor for ZNF238. Can actively repress transcription through the recruitment of HDAC activity.
化学信息
分子量Theoretical: 102 kDa. Actual: 130 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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