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Anti-PAPOLB Polyclonal Antibody

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货号 TMAB-09975

Anti-PAPOLB Polyclonal Antibody 是一种 Rabbit 抗体,靶向 PAPOLB。Anti-PAPOLB Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-PAPOLB Polyclonal Antibody

Anti-PAPOLB Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-09975

Anti-PAPOLB Polyclonal Antibody 是一种 Rabbit 抗体,靶向 PAPOLB。Anti-PAPOLB Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍


生物活性
产品描述
Anti-PAPOLB Polyclonal Antibody is a Rabbit antibody targeting PAPOLB. Anti-PAPOLB Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Pig,Cow,Rabbit)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nuclear
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Polyadenylation of the 3-prime ends of eukaryotic mRNAs is a key event that takes place in the nucleus during maturation of mRNA. The reaction includes endoribonucleolytic cleavage of the pre-RNA at the poly(A) site that leads to synthesis of the poly(A) tail at the 3-prime end of the upstream cleavage product. The poly(A) polymerase (PAP) is required The adenosine addition reaction depends on poly(A) polymerase (PAP) activity. The testis express PAP-Beta (TPAP) in the cytoplasm of spermatogenic cells. The adenosine addition function of PAP-Beta plays a critical role in male germ cell production. PAP-Beta-deficient transgenic mice display impaired expression of haploid-specific genes that are necessary for spermatogenesis. The intronless gene encoding human PAP-∫ maps to chromosome 7p22.3.
抗原信息
免疫原
KLH conjugated synthetic peptide: human PAPOLB
抗原种属
Human
基因名称
PAPOLB
基因ID
蛋白名称
Poly(A) polymerase beta
Uniprot ID
功能
RelevanceThe function of this protein remains unknown. This gene is a member of the myotubularin family and encodes a putative tyrosine phosphatase. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4B, an autosomal recessive demyelinating neuropathy. Multiple alternatively spliced transcript variants have been found for this gene, but the protein products of some of these variants are likely not viable, as they are nonsense-mediated mRNA decay (NMD) candidates.
化学信息
分子量Theoretical: 72 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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