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Anti-IASPP Polyclonal Antibody 是一种 Rabbit 抗体,靶向 IASPP。Anti-IASPP Polyclonal Antibody 可用于 IHC-P,IHC-Fr,ICC/IF,IF,FCM。
Anti-IASPP Polyclonal Antibody 是一种 Rabbit 抗体,靶向 IASPP。Anti-IASPP Polyclonal Antibody 可用于 IHC-P,IHC-Fr,ICC/IF,IF,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,175 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 | |
| 200 μL | ¥ 2,780 | 5日内发货 |
| 产品描述 | Anti-IASPP Polyclonal Antibody is a Rabbit antibody targeting IASPP. Anti-IASPP Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF,FCM. |
| Ig Type | IgG |
| 反应种属 | Human,Rat (predicted:Mouse,Dog,Cow,Sheep,GuineaPig) |
| 应用 | IHC-PIHC-FrICC/IFIFFCM |
| 推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500; FCM: 1μg/Test |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm. Nucleus. Note=Predominantly cytoplasmic but also nuclear. |
| 组织特异性 | Highly expressed in heart, placenta and prostate. Weakly expressed in brain, liver, skeletal muscle, testis and peripheral blood leukocyte. |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | iASPP(inhibitor of apoptosis stimulating protein of p53)regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis. Highly expressed in heart, placenta and prostate. Weakly expressed in brain, liver, skeletal muscle, testis and peripheral blood leukocyte. Belongs to the ASPP family. |
| 免疫原 | KLH conjugated synthetic peptide: human IASPP |
| 抗原种属 | Human |
| 基因名称 | PPP1R13L |
| 基因ID | |
| 蛋白名称 | RelA-associated inhibitor |
| Uniprot ID | |
| 功能 | Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis. |
| 分子量 | Theoretical: 89 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |