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Anti-MIF Antibody (9F31)
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产品编号 TMAC-02585
别名 MMIF, macrophage migration inhibitory factor (glycosylation-inhibiting factor), GLIF, GIF
Anti-MIF Antibody (9F31) 是一种 Rabbit 抗体，靶向 MIF。Anti-MIF Antibody (9F31) 可用于 WB,IP,FCM。
Anti-MIF Antibody (9F31)
Anti-MIF Antibody (9F31)
还可以产品编号 TMAC-02585 别名 MMIF, macrophage migration inhibitory factor (glycosylation-inhibiting factor), GLIF, GIF
Anti-MIF Antibody (9F31) 是一种 Rabbit 抗体，靶向 MIF。Anti-MIF Antibody (9F31) 可用于 WB,IP,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,490 | 5日内发货 | |
| 100 μL | ¥ 2,480 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
化学信息
| 产品描述 | Anti-MIF Antibody (9F31) is a Rabbit antibody targeting MIF. Anti-MIF Antibody (9F31) can be used in WB,IP,FCM. |
| 别名 | MMIF, macrophage migration inhibitory factor (glycosylation-inhibiting factor), GLIF, GIF |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse,Rat |
| 验证活性 | 1. Western blot analysis of MIF on different cells lysates using anti-MIF antibody at 1/500 dilution. Positive control: Line 1: Mouse brain, Line 2: Jurkat, Line 3: Hela. 2. Flow cytometric analysis of THP-1 cells with MIF antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody. |
| 应用 | |
| 推荐剂量 | WB: 1:500-2000; IP: 1:10-50; FCM: 1:50-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | Macrophage migration inhibitory factor, known as MIF or glycosylation-inhibiting factor, is a secreted, homotrimeric, pro-inflammatory cytokine that modulates macrophage and T cell function and is an important regulator of host response to infection. MIF is expressed at sites of inflammation, which suggests that it plays a role in regulating macrophage function in host defense. MIF is produced by the pituitary gland and is found in monocytes, macrophages, differentiating immunological cells in the eye lens and brain, and fibroblasts. Elevated levels of MIF protein are detected in the plasma of patients with severe sepsis or septic shock, a condition where MIF influences endotoxic shock by enhancing the production of other inflammatory cytokines including tumor necrosis factor α (TNFα), interleukin-1 (IL-1) and interferon-γ (IFN-γ). MIF promotes the systemic inflammatory response by counter-regulating glucocorticoid-mediated inhibition of immune-cell activation and proinflammatory cytokine production. MIF may mediate tissue destruction through the induction of proteinases. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 12 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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