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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-PPAP2A Polyclonal Antibody

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货号 TMAB-11650

Anti-PPAP2A Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PPAP2A。Anti-PPAP2A Polyclonal Antibody 可用于 FCM。

Anti-PPAP2A Polyclonal Antibody

Anti-PPAP2A Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-11650

Anti-PPAP2A Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PPAP2A。Anti-PPAP2A Polyclonal Antibody 可用于 FCM。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-PPAP2A Polyclonal Antibody is a Rabbit antibody targeting PPAP2A. Anti-PPAP2A Polyclonal Antibody can be used in FCM.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Dog,Cow,Horse,Rabbit,Sheep)
应用FCM
推荐剂量
FCM: 3μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Multi-pass membrane protein.
组织特异性Ubiquitously expressed with highest expression found in prostate. Isoform 1 is predominant in kidney, lung, placenta and liver. Isoform 2 is predominant in heart and pancreas. Found to be down-regulated in colon adenocarcinomas.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景PPAP2A is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is an integral membrane glycoprotein, and has been shown to be a surface enzyme that plays an active role in the hydrolysis and uptake of lipids from extracellular space.
抗原信息
免疫原
KLH conjugated synthetic peptide: human PPAP2A
抗原种属
Human
基因名称
PLPP1
基因ID
8611
蛋白名称
phospholipid phosphatase 1
Uniprot ID
O14494
功能
Broad-specificity phosphohydrolase that dephosphorylates exogenous bioactive glycerolipids and sphingolipids. Catalyzes the conversion of phosphatidic acid (PA) to diacylglycerol (DG). Pivotal regulator of lysophosphatidic acid (LPA) signaling in the cardiovascular system. Major enzyme responsible of dephosphorylating LPA in platelets, which terminates signaling actions of LPA. May control circulating, and possibly also regulate localized, LPA levels resulting from platelet activation. It has little activity towards ceramide-1-phosphate (C-1-P) and sphingosine-1-phosphate (S-1-P). The relative catalytic efficiency is LPA > PA > S-1-P > C-1-P. It's down-regulation may contribute to the development of colon adenocarcinoma.
化学信息
分子量Theoretical: 32 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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