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Anti-BAG3 Antibody (8D844)

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产品编号 TMAH-00102
别名 MFM6, Docking protein CAIR-1, Docking protein CAIR 1, CAIR 1, BIS, Bcl-2-binding protein Bis, Bcl-2-associated athanogene 3, BCL2 binding athanogene 3, BCL2 associated athanogene 3, Bcl 2 binding protein, BAG family molecular chaperone regulator 3, BAG 3

Anti-BAG3 Antibody (8D844) 是一种抗体,靶向 BAG3。Anti-BAG3 Antibody (8D844) 可用于 ELISA, WB, IHC。

Anti-BAG3 Antibody (8D844)

Anti-BAG3 Antibody (8D844)

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产品编号 TMAH-00102 别名 MFM6, Docking protein CAIR-1, Docking protein CAIR 1, CAIR 1, BIS, Bcl-2-binding protein Bis, Bcl-2-associated athanogene 3, BCL2 binding athanogene 3, BCL2 associated athanogene 3, Bcl 2 binding protein, BAG family molecular chaperone regulator 3, BAG 3

Anti-BAG3 Antibody (8D844) 是一种抗体,靶向 BAG3。Anti-BAG3 Antibody (8D844) 可用于 ELISA, WB, IHC。

规格价格库存数量
50 μL
¥ 1,310
5日内发货
100 μL
¥ 2,185
5日内发货
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产品介绍

生物活性
产品描述
Anti-BAG3 Antibody (8D844) is an antibody targeting BAG3. Anti-BAG3 Antibody (8D844) can be used in ELISA, WB, IHC.
别名MFM6, Docking protein CAIR-1, Docking protein CAIR 1, CAIR 1, BIS, Bcl-2-binding protein Bis, Bcl-2-associated athanogene 3, BCL2 binding athanogene 3, BCL2 associated athanogene 3, Bcl 2 binding protein, BAG family molecular chaperone regulator 3, BAG 3
Ig Type
Rabbit IgG
克隆号
8D844
交叉反应
Human
验证活性
1. Western Blot
-Positive WB detected in: Hela whole cell lysate, 293 whole cell lysate, A549 whole cell lysate, HepG2 whole cell lysate, U87 whole cell lysate
-All lanes: BAG3 antibody at 0.73μg/ml
-Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution
-Predicted band size: 62 KDa
-Observed band size: 80 KDa
2. IHC image of TMAH-00102 diluted at 1:73.75 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
应用
ELISA, WB, IHC
推荐剂量
WB:1:500-1:5000; IHC:1:50-1:200.
抗体种类
Monoclonal
亚细胞定位Nucleus. Cytoplasm.
构建方式Recombinant Antibody
纯化方式Affinity-chromatography
性状Liquid
缓冲液Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release. Nucleotide release is mediated via its binding to the nucleotide-binding domain (NBD) of HSPA8/HSC70 where as the substrate release is mediated via its binding to the substrate-binding domain (SBD) of HSPA8/HSC70. Has anti-apoptotic activity. Plays a role in the HSF1 nucleocytoplasmic transport.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
A synthetic peptide: Human BAG3
抗原种属
Human
基因ID
9531
Uniprot ID
研究领域
Cell Biology
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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