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Anti-PRP19 Antibody (7U313)

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Anti-PRP19 Antibody (7U313)
产品编号 TMAC-03446
别名 UBOX4, SNEV, Senescence evasion factor, psoralen 4, PSO4, PRPF19, PRP19_HUMAN, PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae), PRP19/PSO4 homolog, PRP 19, Pre-mRNA-processing factor 19, pre mRNA processing factor 19, Nuclear matrix protein NMP200 related to splicing factor PRP19, Nuclear matrix protein 200, NMP200, hPso4

Anti-PRP19 Antibody (7U313) 是一种 Rabbit 抗体,靶向 PRP19。Anti-PRP19 Antibody (7U313) 可用于 WB,ICC,IHC,FCM。

Anti-PRP19 Antibody (7U313)

Anti-PRP19 Antibody (7U313)

Rating icon 还可以
Anti-PRP19 Antibody (7U313)
产品编号 TMAC-03446 别名 UBOX4, SNEV, Senescence evasion factor, psoralen 4, PSO4, PRPF19, PRP19_HUMAN, PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae), PRP19/PSO4 homolog, PRP 19, Pre-mRNA-processing factor 19, pre mRNA processing factor 19, Nuclear matrix protein NMP200 related to splicing factor PRP19, Nuclear matrix protein 200, NMP200, hPso4

Anti-PRP19 Antibody (7U313) 是一种 Rabbit 抗体,靶向 PRP19。Anti-PRP19 Antibody (7U313) 可用于 WB,ICC,IHC,FCM。

规格价格库存数量
50 μL
¥ 1,485
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-PRP19 Antibody (7U313) is a Rabbit antibody targeting PRP19. Anti-PRP19 Antibody (7U313) can be used in WB,ICC,IHC,FCM.
别名UBOX4, SNEV, Senescence evasion factor, psoralen 4, PSO4, PRPF19, PRP19_HUMAN, PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae), PRP19/PSO4 homolog, PRP 19, Pre-mRNA-processing factor 19, pre mRNA processing factor 19, Nuclear matrix protein NMP200 related to splicing factor PRP19, Nuclear matrix protein 200, NMP200, hPso4
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of PRP19 on Jurkat cells lysates using anti-PRP19 antibody at 1/1,000 dilution.
2. Immunohistochemical analysis of paraffin-embedded human lung cancer tissue using anti-PRP19 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-PRP19 antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-PRP19 antibody. Counter stained with hematoxylin.
5. Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-PRP19 antibody. Counter stained with hematoxylin.
6. Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-PRP19 antibody. Counter stained with hematoxylin.
7. ICC staining PRP19 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
8. ICC staining PRP19 in B16-F1 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
9. ICC staining PRP19 in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
10. Flow cytometric analysis of Hela cells with PRP19 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
应用
推荐剂量
WB: 1:1000-2000; IHC: 1:50-200; ICC: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景The spliceosome, the 0gigantic molecular machine that performs pre-mRNA splicing in eukaryotes, contains over 200 different proteins and five RNA molecules (U1, U2, U4, U5 and U6). Pre-mRNA splicing is essential to remove internal non-coding regions of pre-mRNA (introns) and to join the remaining segments (exons) into mRNA before translation. The PRP19-associated complex is required for stable association of U5 and U6 with the spliceosome after U4 is released. Changes within the spliceosome upon binding of the PRP19-associated complex include remodeling of the U6/5' splice site interaction and destabilization of Lsm proteins to allow further interaction of U6 with the intron sequence.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
化学信息
分子量Theoretical: 55 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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