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别名 PSMAFGCP, PSMA, PSM, NAALADase I, NAALAdase, NAALAD1, mGCP, GIG27, GCPIImGCP, GCPII, GCP2, FOLHNAALADase I, FOLH1, FOLH, Folate hydrolase 1, FGCP
Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate, roughly a hundred times greater than in most other tissues. In some prostate cancers, PSMA is the second-most upregulated gene product, with an 8- to 12-fold increase over levels in noncancerous prostate cells. PSMA Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 80.6 kDa and the accession number is A0A2K5VNZ0.

Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate, roughly a hundred times greater than in most other tissues. In some prostate cancers, PSMA is the second-most upregulated gene product, with an 8- to 12-fold increase over levels in noncancerous prostate cells. PSMA Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 80.6 kDa and the accession number is A0A2K5VNZ0.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 388 | 现货 | |
| 10 μg | ¥ 625 | 现货 | |
| 20 μg | ¥ 987 | 现货 | |
| 50 μg | ¥ 1,980 | 现货 | |
| 100 μg | ¥ 3,400 | 现货 | |
| 200 μg | ¥ 6,160 | 5日内发货 | |
| 500 μg | ¥ 13,600 | 5日内发货 |
| 产品描述 | Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate, roughly a hundred times greater than in most other tissues. In some prostate cancers, PSMA is the second-most upregulated gene product, with an 8- to 12-fold increase over levels in noncancerous prostate cells. PSMA Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 80.6 kDa and the accession number is A0A2K5VNZ0. |
| 生物活性 | Immobilized Cynomolgus PSMA, His Tag at 2μg/ml (100μl/Well) on the plate. Dose response curve for Anti-PSMA Antibody, hFc Tag with the EC50 of 5.0ng/ml determined by ELISA (QC Test). |
| 研究背景 | Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate, roughly a hundred times greater than in most other tissues. In some prostate cancers, PSMA is the second-most upregulated gene product, with an 8- to 12-fold increase over levels in noncancerous prostate cells. |
| 种属 | Cynomolgus |
| 表达系统 | HEK293 Cells |
| 标签 | N-His |
| 蛋白编号 | A0A2K5VNZ0 |
| 蛋白构建 | Lys44-Ala750 |
| 蛋白纯度 | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| 蛋白性状 | Solution |
| 缓冲液 | Supplied as 0.22 μm filtered solution in PBS (pH 7.4). |
| 别名 | PSMAFGCP, PSMA, PSM, NAALADase I, NAALAdase, NAALAD1, mGCP, GIG27, GCPIImGCP, GCPII, GCP2, FOLHNAALADase I, FOLH1, FOLH, Folate hydrolase 1, FGCP |
| 内毒素 | < 1 EU/μg by the LAL method. |
| 分子量 | 80.6 kDa (predicted). Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result. |
| 颜色 | White |
| 物理性状 | Lyophilized powder |
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
| 存储 | It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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