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Anti-MAPT Antibody (5I591)
还可以产品编号 TMAH-00737
别名 TAU and MAPT, Paired helical filament-tau, Neurofibrillary tangle protein, MTBT1, Microtubule-associated protein tau, MAPTL
Anti-MAPT Antibody (5I591) 是一种抗体，靶向 MAPT。Anti-MAPT Antibody (5I591) 可用于 ELISA, FC。
Anti-MAPT Antibody (5I591)
Anti-MAPT Antibody (5I591)
还可以产品编号 TMAH-00737 别名 TAU and MAPT, Paired helical filament-tau, Neurofibrillary tangle protein, MTBT1, Microtubule-associated protein tau, MAPTL
Anti-MAPT Antibody (5I591) 是一种抗体，靶向 MAPT。Anti-MAPT Antibody (5I591) 可用于 ELISA, FC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,315 | 5日内发货 | |
| 100 μL | ¥ 2,195 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-MAPT Antibody (5I591) is an antibody targeting MAPT. Anti-MAPT Antibody (5I591) can be used in ELISA, FC. |
| 别名 | TAU and MAPT, Paired helical filament-tau, Neurofibrillary tangle protein, MTBT1, Microtubule-associated protein tau, MAPTL |
| Ig Type | Mouse IgG2a |
| 克隆号 | 5I591 |
| 交叉反应 | Human |
| 验证活性 | Overlay Peak curve showing MCF7 cells stained with TMAH-00737 (red line) at 1:100. The cells were fixed in 4% formaldehyde (15min) and permeated by 0.2% TritonX-100 for 10min. Then 10% normal goat serum was Incubated to block non-specific protein-protein interactions followed by the antibody (1µg/1*10^6 cells) for 45 min at 4°C. The secondary antibody used was FITC-conjugated Goat Anti-Mouse IgG(H+L) at 1/200 dilution for 35 min at 4°C. Isotype control antibody (green line) was mouse IgG1 (1µg/1*10^6 cells) used under the same conditions. Acquisition of >10, 000 events was performed. |
| 应用 | ELISA, FC |
| 推荐剂量 | FC:1:20-1:500. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell projection, axon. Cell projection, dendrite. Secreted. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
| 研究背景 | Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: Human MAPT Protein |
| 抗原种属 | Human |
| 基因ID | 4137 |
| Uniprot ID | |
| 研究领域 | Neuroscience, Signal transduction |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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