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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-CD146 Antibody (6H329)

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货号 TMAB-03853

Anti-CD146 Antibody (6H329) 是一种 Rabbit 抗体，靶向 CD146。Anti-CD146 Antibody (6H329) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,IP,FCM。

Anti-CD146 Antibody (6H329)

Anti-CD146 Antibody (6H329)

一键复制产品信息
Rating icon 还可以
货号 TMAB-03853

Anti-CD146 Antibody (6H329) 是一种 Rabbit 抗体，靶向 CD146。Anti-CD146 Antibody (6H329) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,IP,FCM。

规格价格库存数量
25 μL
¥ 780
5日内发货
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-CD146 Antibody (6H329) is a Rabbit antibody targeting CD146. Anti-CD146 Antibody (6H329) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,IP,FCM.
Ig Type
IgG
克隆号
6H329
反应种属
Human,Mouse,Rat
应用WBIHC-PIHC-FrICC/IFIFIPFCM
推荐剂量
WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; ICC/IF: 1:50-200; IF: 1:50-200; IP: 1:20-50; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Membrane; Single-pass type I membrane protein.
组织特异性Detected in endothelial cells in vascular tissue throughout the body. May appear at the surface of neural crest cells during their embryonic migration. Appears to be limited to vascular smooth muscle in normal adult tissues. Associated with tumor progression and the development of metastasis in human malignant melanoma. Expressed most strongly on metastatic lesions and advanced primary tumors and is only rarely detected in benign melanocytic nevi and thin primary melanomas with a low probability of metastasis.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景CD146 plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development.
抗原信息
免疫原
A synthesized peptide: human MCAM
抗原种属
Human
基因名称
MCAM
基因ID
4162
蛋白名称
Cell surface glycoprotein MUC18
Uniprot ID
P43121
功能
Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.
化学信息
分子量Theoretical: 72 kDa. Actual: 72 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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