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Anti-Influenza A virus Nucleoprotein H1N1 Antibody (9T39)

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货号 TMAB-07699

Anti-Influenza A virus Nucleoprotein H1N1 Antibody (9T39) 是一种 Mouse 抗体,靶向 Influenza A virus Nucleoprotein H1N1。Anti-Influenza A virus Nucleoprotein H1N1 Antibody (9T39) 可用于 WB。

Anti-Influenza A virus Nucleoprotein H1N1 Antibody (9T39)

Anti-Influenza A virus Nucleoprotein H1N1 Antibody (9T39)

一键复制产品信息
Rating icon 还可以
货号 TMAB-07699

Anti-Influenza A virus Nucleoprotein H1N1 Antibody (9T39) 是一种 Mouse 抗体,靶向 Influenza A virus Nucleoprotein H1N1。Anti-Influenza A virus Nucleoprotein H1N1 Antibody (9T39) 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
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100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍


生物活性
产品描述
Anti-Influenza A virus Nucleoprotein H1N1 Antibody (9T39) is a Mouse antibody targeting Influenza A virus Nucleoprotein H1N1. Anti-Influenza A virus Nucleoprotein H1N1 Antibody (9T39) can be used in WB.
Ig Type
IgG
克隆号
9T39
反应种属
Influenza A Nucleoprotein [A/Victoria/4897/2022 (H1N1)]
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Virion membrane. Host apical cell membrane; Single-pass type III membrane protein. Note=Abundantly expressed at the apical plasma membrane in infected polarized epithelial cells, in close proximity to budding and assembled virions. Minor component of virions (only 16-20 molecules/virion).
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The nucleoprotein (NP) of Influenza virus encapsulates the negative strand of the viral RNA and is essential for replicative transcription. It may also be involved in other essential functions throughout the virus life cycle. As well as binding ssRNA, NP is able to self associate to form large oligomeric complexes. NP is able to interact with a variety of other macromolecules of both viral and cellular origins. It binds the PB1 and PB2 subunits of the polymerase and the matrix protein M1. "NP has also been shown to interact with at least four cellular polypeptide families: nuclear import receptors of the importin class, filamentous (F) actin, the nuclear export receptor CRM1 and a DEAD box helicase BAT1/UAP56" (Portela et al 2002).
抗原信息
免疫原
Recombinant Protein: Influenza A virus H1N1(A/Victoria/4897/2022)Nucleoprotein
抗原种属
Influenza A virus
基因名称
NP
基因ID
蛋白名称
Nucleoprotein
功能
Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry. After attaching to the cell surface, the virion enters the cell by endocytosis. Acidification of the endosome triggers M2 ion channel activity. The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins and enabling RNA segments to migrate to the host cell nucleus, where influenza virus RNA transcription and replication occur. Also plays a role in viral proteins secretory pathway. Elevates the intravesicular pH of normally acidic compartments, such as trans-Golgi network, preventing newly formed hemagglutinin from premature switching to the fusion-active conformation.
化学信息
分子量Theoretical: 57 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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