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Anti-MCP-3/CCL7 Antibody-PE (4B549)
还可以产品编号 TMAY-02144P
Anti-MCP-3/CCL7 Antibody-PE (4B549) 是一种 PE-conjugated Mouse 抗体，靶向 MCP-3/CCL7。Anti-MCP-3/CCL7 Antibody-PE (4B549) 可用于 FCM。
Anti-MCP-3/CCL7 Antibody-PE (4B549)
Anti-MCP-3/CCL7 Antibody-PE (4B549)
还可以产品编号 TMAY-02144P
Anti-MCP-3/CCL7 Antibody-PE (4B549) 是一种 PE-conjugated Mouse 抗体，靶向 MCP-3/CCL7。Anti-MCP-3/CCL7 Antibody-PE (4B549) 可用于 FCM。
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| 产品描述 | Anti-MCP-3/CCL7 Antibody-PE (4B549) is a PE-conjugated Mouse antibody targeting MCP-3/CCL7. Anti-MCP-3/CCL7 Antibody-PE (4B549) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 4B549 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of Human CCL7 expression on THP1 cells. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), and then stained with PE-conjugated anti-Human CCL7. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| 应用 | FCM |
| 推荐剂量 | 10 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human MCP-3 / CCL7 (rh MCP-3 / CCL7; NP_006264.2Gln24-Leu99) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| 研究背景 | Chemokines are a family of small chemotactic cytokines, or proteins secreted by cells. Chemokines share the same structure similarities such as small size, and the presence of four cysteine residues in conserved locations in order to form their 3-dimensional shape. Some of the chemokines are considered pro-inflammatory which can be induced to recruit cells of the immune system to a site of infection during an immune response, while others are considered homeostatic and are implied in controlling the migration of cells during normal processes of tissue maintenance and development. There are four members of the chemokine family: C-C kemokines, C kemokines, CXC kemokines and CX3C kemokines. The C-C kemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands-1 to 28. Chemokine ligand 7(CCL7), also known as MCP-3, is a isform of the C-C chemokine subfamily of the chemokine family which is produced by certain tumor cells and by macrophages. It also own two adjacent N-terminal cysteine residues. Chemokine ligand 7(CCL7) spacifically attracts monocytes, and regulates macrophage function. |
| 偶联 | PE |
| 其他可选修饰符 | Unconjugated |
| 可提供抗体种类 | 2 |
| 免疫原 | Recombinant Human MCP-3 / CCL7 protein |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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