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Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15. GDF-15 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 13.68 kDa and the accession number is Q9Z0J6.

| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 493 | 6-8日内发货 | |
| 10 μg | ¥ 786 | 6-8日内发货 | |
| 20 μg | ¥ 1,330 | 5日内发货 | |
| 50 μg | ¥ 2,630 | 5日内发货 | |
| 100 μg | ¥ 4,430 | In stock | |
| 200 μg | ¥ 7,900 | 5日内发货 | |
| 500 μg | ¥ 17,800 | 5日内发货 |
| 生物活性 | 1. Immobilized Rat GDF-15, His Tag at 5 μg/mL (100 μL/well) on the plate. Dose response curve for Human GFRAL, hFc Tag with the EC50 of 8.0 ng/mL determined by ELISA._x000D_
2. Immobilized Rat GDF15, His Tag at 5 μg/mL (100 μL/well) on the plate. Dose response curve for Biotinylated Mouse GFRAL, His Tag with the EC50 of 0.95 μg/mL determined by ELISA. ![]() ![]() |
| 产品描述 | Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15. GDF-15 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 13.68 kDa and the accession number is Q9Z0J6. |
| 种属 | Rat |
| 表达系统 | E. coli |
| 标签 | N-His |
| 蛋白编号 | Q9Z0J6 |
| 别名 | RG-1,PTGF-β,PTGFBPTGF-β,PTGFBPTGF-beta,PTGF-beta,PTGFB,Placental TGF-β,Placental TGF-beta,PLAB,PDF,NAG-1,MIC-1,MIC1,GDF-15,GDF15 |
| 蛋白构建 | Ser189-Ala303 |
| 蛋白纯度 | > 95% as determined by Tris-Bis PAGE ![]() |
| 分子量 | 13.68 kDa (predicted). The protein migrates to 15-17 kDa based on Tris-Bis PAGE result. |
| 内毒素 | < 1 EU/μg by the LAL method. |
| 蛋白性状 | Lyophilized powder |
| 缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing 50 mM HAc (pH 2.9). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
| 复溶方法 | Reconstitute the lyophilized protein in 50mM HAc (pH 2.9). The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| 存储 | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. |
| 研究背景 | Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15. |