IL-13 Protein, Mouse, Recombinant (aa 26-131, His)

IL-13 Protein, Mouse, Recombinant (aa 26-131, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 15-30 KDa and the accession number is P20109.

规格	价格/CNY		数量
10 μg	￥ 1,170	现货
50 μg	￥ 3,470	5日内发货
500 μg	￥ 15,000	5日内发货
1 mg	￥ 24,100	5日内发货

规格

价格/CNY

货期

数量

10 μg

￥ 1,170

现货

50 μg

￥ 3,470

5日内发货

500 μg

￥ 15,000

5日内发货

1 mg

￥ 24,100

5日内发货

生物活性	Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. The ED50 for this effect is 2-13 ng/ml. (QC verified)
产品描述	IL-13 Protein, Mouse, Recombinant (aa 26-131, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 15-30 KDa and the accession number is P20109.

种属	Mouse
表达系统	HEK293 Cells
标签	C-6xHis
蛋白编号	P20109
别名	Interleukin-13, T-Cell Activation Protein P600, 白细胞介素, IL-13, Il13, 白介素
氨基酸序列	Ser26-Phe131
蛋白构建	Ser26-Phe131
蛋白纯度	Greater than 95% as determined by reducing SDS-PAGE. Greater than 95% as determined by SEC-HPLC.
分子量	15-30 KDa (reducing condition)

内毒素	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	Mouse interleukin 13 (mIL-13) is a pleiotropic cytokine produced by activated Th2 cells. IL-13 induces B cell proliferation and immunoglobin production. It contains a four helical bundle with two internal disulfide bonds. Mouse IL13 shares 58% sequence identity with human protein and exhibits cross-species activity. IL13 signals via receptor IL13R (type2, IL4R) and activates STAT-6. IL13 initially binds IL-13Rα1 with low affinity and triggers association of IL4Rα, generating a high affinity heterodimeric receptor IL13R and eliciting downstream signals. IL13 also binds IL-13Rα2 with high affinity, which plays a role in a negative feedback system of IL13 signaling. IL13 is an important mediator of allergic inflammation and disease.

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IL-13 Protein, Mouse, Recombinant (aa 26-131, His)

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