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Anti-Thioredoxin 2/TRX2 Antibody (7F674)
还可以产品编号 TMAY-02379
Anti-Thioredoxin 2/TRX2 Antibody (7F674) 是一种 Rabbit 抗体，靶向 Thioredoxin 2/TRX2。Anti-Thioredoxin 2/TRX2 Antibody (7F674) 可用于 IHC-P。
Anti-Thioredoxin 2/TRX2 Antibody (7F674)
Anti-Thioredoxin 2/TRX2 Antibody (7F674)
还可以产品编号 TMAY-02379
Anti-Thioredoxin 2/TRX2 Antibody (7F674) 是一种 Rabbit 抗体，靶向 Thioredoxin 2/TRX2。Anti-Thioredoxin 2/TRX2 Antibody (7F674) 可用于 IHC-P。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Thioredoxin 2/TRX2 Antibody (7F674) is a Rabbit antibody targeting Thioredoxin 2/TRX2. Anti-Thioredoxin 2/TRX2 Antibody (7F674) can be used in IHC-P. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 7F674 |
| 交叉反应 | Human |
| 验证活性 | 1. Immunochemical staining of human TXN2 in human small intestine with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human TXN2 in human kidney with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). |
| 应用 | IHC-P |
| 推荐剂量 | IHC-P: 1:100-1:500 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human Thioredoxin-2 / TXN2 (rh Thioredoxin-2 / TXN2; TMPY-02084; Q99757; Thr60-Gly166). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Thioredoxin-2, also known as TXN2, MTRX and TRX2, is a member of the thioredoxin family. Tryparedoxins (TXN) are thioredoxin-related proteins which, as trypanothione:peroxiredoxin oxidoreductases, constitute the trypanothione-dependent antioxidant defense and may also serve as substrates for ribonucleotide reductase in trypanosomatids. Thioredoxin-2 / TXN2 contains one thioredoxin domain. It is widely expressed in adult (at protein level) and fetal tissues. Human Thioredoxin-2 / TXN2 is a small redox protein important in cellular antioxidant defenses, as well as in the regulation of apoptosis. Thioredoxin-2 / TXN2 has an anti-apoptotic function and plays an important role in the regulation of mitochondrial membrane potential. Thioredoxin-2 / TXN2 could be involved in the resistance to anti-tumor agents. It possesses a dithiol-reducing activity. Thioredoxin-2 / TXN2 plays an important role in protecting the mitochondria against oxidative stress and in sensitizing the cells to ROS-induced apoptosis. Mammalian Thioredoxin-2 / TXN2 is a mitochondrial isoform of highly evolutionary conserved thioredoxins. Thioredoxins are small ubiquitous protein-disulfide oxidoreductases implicated in a large variety of biological functions. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human Thioredoxin-2 / TXN2 protein (TMPY-02084) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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