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Anti-Serpin A3 Antibody (4O903)

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产品编号 TMAY-00594

Anti-Serpin A3 Antibody (4O903) 是一种 Rabbit 抗体,靶向 Serpin A3。Anti-Serpin A3 Antibody (4O903) 可用于 ELISA(Cap)。

Anti-Serpin A3 Antibody (4O903)

Anti-Serpin A3 Antibody (4O903)

Rating icon 还可以
产品编号 TMAY-00594

Anti-Serpin A3 Antibody (4O903) 是一种 Rabbit 抗体,靶向 Serpin A3。Anti-Serpin A3 Antibody (4O903) 可用于 ELISA(Cap)。

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产品介绍

生物活性
产品描述
Anti-Serpin A3 Antibody (4O903) is a Rabbit antibody targeting Serpin A3. Anti-Serpin A3 Antibody (4O903) can be used in ELISA(Cap).
Ig Type
Monoclonal Rabbit IgG
克隆号
4O903
交叉反应
Human
应用
ELISA(Cap)
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human SerpinA3 (rh SerpinA3; TMPY-01303; NP_001076.2; Met1-Ala423).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景SerpinA3, also known as Alpha 1-antichymotrypsin (AACT), is a plasma alpha globulin glycoprotein, and is a member of serpin superfamily of the serine protease inhibitors consisting of at least 35 members. SerpinA3 has been demonstrated to inhibit the activity of certain serine proteases, such as cathepsin G found in neutrophils, and chymases present in mast cells, by inducing a major conformational rearrangement, and thus protects some tissues from damage caused by proteolytic enzymes. This enzyme is produced primarily in the liver, and is identified as an acute-phase inflammatory protein. SerpinA3 deficiency has been associated with liver disease, and mutations of this gene have been observed in patients with Parkinson disease and chronic obstructive pulmonary disease. Besides, ACT gene polymorphism has been implicated with Alzheimer’s disease (AD), cerebral amyloid angiopathy (CAA), as well as stroke, since SerpinA3 is a major constituent of the plaques in AD and an inhibitor of amyloid beta peptide degradation.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Human SerpinA3 Protein (TMPY-01303)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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