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Anti-MAVS Polyclonal Antibody

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货号 TMAB-01107

别名 VISA, Virus induced signaling adapter, Putative NF kappa B activating protein 031N, Mitochondrial Antiviral Signaling, Mitochondrial anti viral signaling protein, MGC3260, MAVS, KIAA1271, IPS-1, IPS1, Ips1, Ips 1, Interferon-beta promoter stimulator protein 1, Interferon β promoter stimulator protein 1, FLJ41962, FLJ38051, FLJ35386, FLJ31698, FLJ27482, DKFZp666M015, DKFZp547C224, CARDIF, Cardif, CARD adapter inducing interferon beta

Anti-MAVS Polyclonal Antibody 是一种 Rabbit 抗体，靶向 MAVS。Anti-MAVS Polyclonal Antibody 可用于 WB。

Anti-MAVS Polyclonal Antibody

Anti-MAVS Polyclonal Antibody

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货号 TMAB-01107 别名 VISA, Virus induced signaling adapter, Putative NF kappa B activating protein 031N, Mitochondrial Antiviral Signaling, Mitochondrial anti viral signaling protein, MGC3260, MAVS, KIAA1271, IPS-1, IPS1, Ips1, Ips 1, Interferon-beta promoter stimulator protein 1, Interferon β promoter stimulator protein 1, FLJ41962, FLJ38051, FLJ35386, FLJ31698, FLJ27482, DKFZp666M015, DKFZp547C224, CARDIF, Cardif, CARD adapter inducing interferon beta

Anti-MAVS Polyclonal Antibody 是一种 Rabbit 抗体，靶向 MAVS。Anti-MAVS Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

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产品描述
Anti-MAVS Polyclonal Antibody is a Rabbit antibody targeting MAVS. Anti-MAVS Polyclonal Antibody can be used in WB.
别名VISA, Virus induced signaling adapter, Putative NF kappa B activating protein 031N, Mitochondrial Antiviral Signaling, Mitochondrial anti viral signaling protein, MGC3260, MAVS, KIAA1271, IPS-1, IPS1, Ips1, Ips 1, Interferon-beta promoter stimulator protein 1, Interferon β promoter stimulator protein 1, FLJ41962, FLJ38051, FLJ35386, FLJ31698, FLJ27482, DKFZp666M015, DKFZp547C224, CARDIF, Cardif, CARD adapter inducing interferon beta
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Cow)
验证活性
Sample:
Liver (Mouse) Lysate at 40 μg
Primary: Anti-MAVS (TMAB-01107) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 56 kDa
Observed band size: 56 kDa
verifiedActivity
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Mitochondrion outer membrane.
组织特异性Present in T-cells, monocytes, epithelial cells and hepatocytes (at protein level). Ubiquitously expressed, with highest levels in heart, skeletal muscle, liver, placenta and peripheral blood leukocytes.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景MAVS (Mitochondrial Antiviral Signaling) mediates the activation of NF-kappaB and IRF3 in response to antiviral infection. Silencing of MAVS expression permits derepression of viral replication, while over expression of MAVS boosts antiviral immunity.
抗原信息
免疫原
KLH conjugated synthetic peptide: human MAVS N terminus
抗原种属
Human
基因名称
MAVS
基因ID
57506
蛋白名称
Mitochondrial antiviral-signaling protein
Uniprot ID
Q7Z434
研究领域
NFkB pathway,Antiviral Signaling,NFkB Pathway
功能
Required for innate immune defense against viruses. Acts downstream of DDX58 and IFIH1/MDA5, which detect intracellular dsRNA produced during viral replication, to coordinate pathways leading to the activation of NF-kappa-B, IRF3 and IRF7, and to the subsequent induction of antiviral cytokines such as IFN-beta and RANTES (CCL5). May activate the same pathways following detection of extracellular dsRNA by TLR3. May protect cells from apoptosis.
化学信息
分子量Theoretical: 56 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | store at -20°C

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