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Anti-BCL6 Polyclonal Antibody

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产品编号 TMAB-00201

别名 ZNF51, ZBTB27, LAZ3, BCL6A, BCL5, B-cell CLL/lymphoma 6

Anti-BCL6 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 BCL6。Anti-BCL6 Polyclonal Antibody 可用于 ELISA,IF,IHC-Fr,IHC-P。

Anti-BCL6 Polyclonal Antibody

Anti-BCL6 Polyclonal Antibody

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Rating icon 还可以
产品编号 TMAB-00201 别名 ZNF51, ZBTB27, LAZ3, BCL6A, BCL5, B-cell CLL/lymphoma 6

Anti-BCL6 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 BCL6。Anti-BCL6 Polyclonal Antibody 可用于 ELISA,IF,IHC-Fr,IHC-P。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,965
5日内发货
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产品介绍

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产品描述
Anti-BCL6 Polyclonal Antibody is a Rabbit antibody targeting BCL6. Anti-BCL6 Polyclonal Antibody can be used in ELISA,IF,IHC-Fr,IHC-P.
别名ZNF51, ZBTB27, LAZ3, BCL6A, BCL5, B-cell CLL/lymphoma 6
Ig Type
IgG
交叉反应
Human,Mouse
验证活性
Paraformaldehyde-fixed, paraffin embedded (human lung carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Incubation with (Bcl-6) Polyclonal Antibody, Unconjugated (TMAB-00201) at 1:25 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructionsand DAB staining.
verifiedActivity
应用ELISAIFIHC-FrIHC-P
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus (By similarity).
组织特异性Expressed in germinal center T and B-cells and in primary immature dendritic cells.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq].
抗原信息
免疫原
KLH conjugated synthetic peptide: human Bcl-6
抗原种属
Human
基因名称
BCL6
基因ID
蛋白名称
B-cell lymphoma 6 protein
Uniprot ID
研究领域
Transcription factors,Proto-oncogenes,Zinc Finger
功能
Transcriptional repressor which is required for germinal center formation and antibody affinity maturation. Probably plays an important role in lymphomagenesis.
化学信息
分子量Theoretical: 78 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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