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Anti-Uteroglobin Antibody (9A494)

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货号 TMAY-03214

别名 Utg, UGB, UG, secretoglobin, family 1A, member 1 (uteroglobin), PCB-BP, CCSP, CC16, CC10

Anti-Uteroglobin Antibody (9A494) 是一种 Rabbit 抗体，靶向 Uteroglobin。Anti-Uteroglobin Antibody (9A494) 可用于 IHC-P。

Anti-Uteroglobin Antibody (9A494)

Anti-Uteroglobin Antibody (9A494)

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Rating icon 还可以
货号 TMAY-03214 别名 Utg, UGB, UG, secretoglobin, family 1A, member 1 (uteroglobin), PCB-BP, CCSP, CC16, CC10

Anti-Uteroglobin Antibody (9A494) 是一种 Rabbit 抗体，靶向 Uteroglobin。Anti-Uteroglobin Antibody (9A494) 可用于 IHC-P。

规格价格库存数量
100 μL
¥ 2,279
5日内发货
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产品介绍

生物活性
产品描述
Anti-Uteroglobin Antibody (9A494) is a Rabbit antibody targeting Uteroglobin. Anti-Uteroglobin Antibody (9A494) can be used in IHC-P.
别名Utg, UGB, UG, secretoglobin, family 1A, member 1 (uteroglobin), PCB-BP, CCSP, CC16, CC10
Ig Type
Rabbit IgG
克隆号
9A494
反应种属
Mouse
特异性
Mouse Uteroglobin
No cross-reactivity in ELISA with
Human SCGB1A1
验证活性
Immunochemical staining of mouse SCGB1A1 in mouse lung with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).
应用IHC-P
推荐剂量
IHC-P: 1:100-1:500
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Uteroglobin / SCGB1A1 (rM Uteroglobin / SCGB1A1; TMPY-02328; Q06318; Met1-Phe96).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Uteroglobin (UG), also known as Secretoglobin 1A member 1 (SCGB1A1), Blastokinin, Clara cell secretor protein (CCSP) or Clara cell-specific 10-kDa protein (CC10), is the founding member of the secretoglobin family of small, secreted, disulfide-bridged dimeric proteins found only in mammals. This protein is mainly expressed in lung, with anti-inflammatory/immunomodulatory properties. Previous in vitro studies demonstrated that CCAAT/enhancer-binding proteins (C/EBPs) are the major transcription factors for the regulation of SCGB1A1 gene expression, whereas FOXA1 had a minimum effect on the transcription. Uteroglobin is a multifunctional protein with antiinflammatory/immunomodulatory properties. Uteroglobin inhibits soluble phospholipase A(2) activity and binds and perhaps sequesters hydrophobic ligands such as progesterone, retinols, polychlorinated biphenyls, phospholipids, and prostaglandins. In addition to its antiinflammatory activities, Uteroglobin manifests antichemotactic, antiallergic, antitumorigenic, and embryonic growth-stimulatory activities. The tissue-specific expression of the Uteroglobin gene is regulated by several steroid hormones, although a nonsteroid hormone, prolactin, further augments its expression in the uterus. Based on its anti-inflammatory and antiallergic properties, Uteroglobin is a potential drug target. The mechanism of Uteroglobin action is likely to be even more complex as it also functions via a putative receptor-mediated pathway.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Mouse Uteroglobin / SCGB1A1 protein (TMPY-02328)
抗原种属
Mouse
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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关键词

uteroglobinsecretoglobin, family 1A, member 1CC-16CC-10CC 16CC 10
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