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Anti-Phospho-BTK (Tyr223) Polyclonal Antibody

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Anti-Phospho-BTK (Tyr223) Polyclonal Antibody
产品编号 TMAC-00484
别名 p-BTK (Y223), p-BTK (Tyr223), BTK (p-Y223), BTK (p-Tyr223)

Anti-Phospho-BTK (Tyr223) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-BTK (Tyr223)。Anti-Phospho-BTK (Tyr223) Polyclonal Antibody 可用于 WB。

Anti-Phospho-BTK (Tyr223) Polyclonal Antibody

Anti-Phospho-BTK (Tyr223) Polyclonal Antibody

Rating icon 还可以
Anti-Phospho-BTK (Tyr223) Polyclonal Antibody
产品编号 TMAC-00484 别名 p-BTK (Y223), p-BTK (Tyr223), BTK (p-Y223), BTK (p-Tyr223)

Anti-Phospho-BTK (Tyr223) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-BTK (Tyr223)。Anti-Phospho-BTK (Tyr223) Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,480
5日内发货
100 μL
¥ 2,245
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-BTK (Tyr223) Polyclonal Antibody is a Rabbit antibody targeting Phospho-BTK (Tyr223). Anti-Phospho-BTK (Tyr223) Polyclonal Antibody can be used in WB.
别名p-BTK (Y223), p-BTK (Tyr223), BTK (p-Y223), BTK (p-Tyr223)
Ig Type
IgG
交叉反应
Human,Mouse
验证活性
1. Western blot analysis of extracts from Hela cells treated with serum using BTK (phospho-Tyr223) Antibody TMAC-00484.The lane on the right is treated with the antigen-specific peptide.
应用
WB
推荐剂量
WB: 1:500-1000
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Polyclonal Antibody
纯化方式Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
性状Liquid
缓冲液Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Non-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. After BCR engagement and activation at the plasma membrane, phosphorylates PLCG2 at several sites, igniting the downstream signaling pathway through calcium mobilization, followed by activation of the protein kinase C (PKC) family members. PLCG2 phosphorylation is performed in close cooperation with the adapter protein B-cell linker protein BLNK.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
Peptide sequence around phosphorylation site of tyrosine 223 (A-L-Y(p)-D-Y) derived from Human BTK
抗原种属
human
Uniprot ID
Q06187
化学信息
分子量Actual: 80 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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关键词

pBTK (Y223)pBTK (Tyr223)BTK (pY223)BTK (pTyr223)BTK (phospho-Y223)BTK (phospho-Tyr223)

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4个月前
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