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Anti-smooth muscle Myosin heavy chain 11 Antibody (2P75) 是一种 Rabbit 抗体,靶向 smooth muscle Myosin heavy chain 11。Anti-smooth muscle Myosin heavy chain 11 Antibody (2P75) 可用于 WB,IHC-P,IF,IHC-Fr。
Anti-smooth muscle Myosin heavy chain 11 Antibody (2P75) 是一种 Rabbit 抗体,靶向 smooth muscle Myosin heavy chain 11。Anti-smooth muscle Myosin heavy chain 11 Antibody (2P75) 可用于 WB,IHC-P,IF,IHC-Fr。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 780 | 5日内发货 | |
| 50 μL | ¥ 1,395 | 5日内发货 | |
| 100 μL | ¥ 2,485 | 5日内发货 |
| 产品描述 | Anti-smooth muscle Myosin heavy chain 11 Antibody (2P75) is a Rabbit antibody targeting smooth muscle Myosin heavy chain 11. Anti-smooth muscle Myosin heavy chain 11 Antibody (2P75) can be used in WB,IHC-P,IF,IHC-Fr. |
| Ig Type | IgG |
| 克隆号 | 2P75 |
| 反应种属 | Human,Mouse,Rat |
| 应用 | WBIHC-PIFIHC-Fr |
| 推荐剂量 | WB: 1:500-2000; IHC-P: 1:100-500; IF: 1:100-500; IHC-Fr: 1:100-500 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Thick filaments of the myofibrils. |
| 组织特异性 | Smooth muscle; expressed in the umbilical artery, bladder, esophagus and trachea. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | The protein encoded by this gene is a smooth muscle myosin belonging to the myosin heavy chain family. The gene product is a subunit of a hexameric protein that consists of two heavy chain subunits and two pairs of non-identical light chain subunits. It functions as a major contractile protein, converting chemical energy into mechanical energy through the hydrolysis of ATP. The gene encoding a human ortholog of rat NUDE1 is transcribed from the reverse strand of this gene, and its 3' end overlaps with that of the latter. The pericentric inversion of chromosome 16[inv(16)(p13q22)] produces a chimeric transcript that encodes a protein consisting of the first 165 residues from the N terminus of core-binding factor beta in a fusion with the C-terminal portion of the smooth muscle myosin heavy chain. This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype. Alternative splicing generates isoforms that are differentially expressed, with ratios changing during muscle cell maturation. Alternatively spliced transcript variants encoding different isoforms have been identified. MYH11 is a smooth muscle myosin belonging to the myosin heavy chain family. It is a subunit of a hexameric protein that consists of two heavy chain subunits and two pairs of non-identical light chain subunits. It functions as a major contractile protein, converting chemical energy into mechanical energy through the hydrolysis of ATP. |
| 免疫原 | A synthesized peptide: human Myosin heavy chain 11 |
| 抗原种属 | Human |
| 基因名称 | MYH11 |
| 基因ID | |
| 蛋白名称 | Myosin-11 |
| Uniprot ID | |
| 功能 | Muscle contraction. |
| 分子量 | Theoretical: 227 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |