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Anti-DOPA Decarboxylase/DDC Antibody (6D706)
还可以产品编号 TMAY-00977
Anti-DOPA Decarboxylase/DDC Antibody (6D706) 是一种 Rabbit 抗体，靶向 DOPA Decarboxylase/DDC。Anti-DOPA Decarboxylase/DDC Antibody (6D706) 可用于 ELISA,IHC-P。
Anti-DOPA Decarboxylase/DDC Antibody (6D706)
Anti-DOPA Decarboxylase/DDC Antibody (6D706)
还可以产品编号 TMAY-00977
Anti-DOPA Decarboxylase/DDC Antibody (6D706) 是一种 Rabbit 抗体，靶向 DOPA Decarboxylase/DDC。Anti-DOPA Decarboxylase/DDC Antibody (6D706) 可用于 ELISA,IHC-P。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-DOPA Decarboxylase/DDC Antibody (6D706) is a Rabbit antibody targeting DOPA Decarboxylase/DDC. Anti-DOPA Decarboxylase/DDC Antibody (6D706) can be used in ELISA,IHC-P. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 6D706 |
| 交叉反应 | Human |
| 验证活性 | Immunochemical staining of human DDC in human brain with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). The left panel: tissue incubated with primary antibody; The right panel: tissue incubated with the mixture of primary antibody and antigen (recombinant protein). |
| 应用 | ELISA,IHC-P |
| 推荐剂量 | ELISA: 1:5000-1:10000; IHC-P: 1:100-1:500 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human DOPA Decarboxylase / DDC (rh DOPA Decarboxylase / DDC; TMPY-01060; NP_000781.1; Met 1-Glu 480). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Dopa Decarboxylase (DDC), also known as AADC and Aromatic-L-amino acid decarboxylase, is a 54 kDa member of the group II decarboxylase family of proteins.It is a vitamin B6-dependent homodimeric enzyme that catalyzes the decarboxylation of both L-3,4-dihydroxyphenylalanine (L-DOPA) and L-5-hydroxytryptophan to dopamine and serotonin, respectively, which are major mammalian neurotransmitters and hormones belonging to catecholamines and indoleamines. Since L-DOPA is regularly used to treat the symptoms of Parkinson's disease, the catalytic pathway is of particular research interest. Defects of DDC are associated with severe developmental delay, oculogyric crises (OGC), as well as autosomal recessive disorder AADC deficiency, an early onset inborn error in neurotransmitter metabolism which can lead to catecholamine and serotonin deficiency. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human DOPA Decarboxylase / DDC protein (TMPY-01060) |
| 抗原种属 | Human |
| 研究领域 | Neurotransmitter Associated Enzymes |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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