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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-PHF2 Polyclonal Antibody

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货号 TMAB-10266

Anti-PHF2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PHF2。Anti-PHF2 Polyclonal Antibody 可用于 IHC-P,WB,IHC-Fr,IF。

Anti-PHF2 Polyclonal Antibody

Anti-PHF2 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-10266

Anti-PHF2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PHF2。Anti-PHF2 Polyclonal Antibody 可用于 IHC-P,WB,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-PHF2 Polyclonal Antibody is a Rabbit antibody targeting PHF2. Anti-PHF2 Polyclonal Antibody can be used in IHC-P,WB,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用IHC-PWBIHC-FrIF
推荐剂量
IHC-P: 1:100-500; WB: 1:500-2000; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus, nucleolus.
组织特异性Widely expressed, including in liver (at protein level).
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a protein which contains a zinc finger-like PHD (plant homeodomain) finger, distinct from other classes of zinc finger motifs, and a hydrophobic and highly conserved domain. The PHD finger shows the typical Cys4-His-Cys3 arrangement. PHD finger genes are thought to belong to a diverse group of transcriptional regulators possibly affecting eukaryotic gene expression by influencing chromatin structure. [provided by RefSeq, Jul 2008]
抗原信息
免疫原
Recombinant Protein: human PHF2 protein
抗原种属
Human
基因名称
PHF2
基因ID
5253
蛋白名称
Lysine-specific demethylase PHF2
Uniprot ID
O75151
功能
Lysine demethylase that demethylates both histones and non-histone proteins. Enzymatically inactive by itself, and becomes active following phosphorylation by PKA: forms a complex with ARID5B and mediates demethylation of methylated ARID5B. Demethylation of ARID5B leads to target the PHF2-ARID5B complex to target promoters, where PHF2 mediates demethylation of dimethylated 'Lys-9' of histone H3 (H3K9me2), followed by transcription activation of target genes. The PHF2-ARID5B complex acts as a coactivator of HNF4A in liver. PHF2 is recruited to trimethylated 'Lys-4' of histone H3 (H3K4me3) at rDNA promoters and promotes expression of rDNA.
化学信息
分子量Theoretical: 121 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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