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Anti-EGF Antibody (9J938)

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Anti-EGF Antibody (9J938)
产品编号 TMAY-01021
别名 表皮生长因子, epidermal growth factor

Anti-EGF Antibody (9J938) 是一种 Rabbit 抗体,靶向 EGF。Anti-EGF Antibody (9J938) 可用于 ELISA。

Anti-EGF Antibody (9J938)
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Anti-EGF Antibody (9J938)

Rating icon 还可以
Anti-EGF Antibody (9J938)
产品编号 TMAY-01021 别名 表皮生长因子, epidermal growth factor

Anti-EGF Antibody (9J938) 是一种 Rabbit 抗体,靶向 EGF。Anti-EGF Antibody (9J938) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 2,294
5日内发货
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产品介绍

生物活性
产品描述
Anti-EGF Antibody (9J938) is a Rabbit antibody targeting EGF. Anti-EGF Antibody (9J938) can be used in ELISA.
别名表皮生长因子, epidermal growth factor
Ig Type
Rabbit IgG
克隆号
9J938
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human EGF(rh EGF; TMPY-01560; NP_001954.2; Asn 971-Arg 1023) .
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景EGF is the founding member of the EGF-family of proteins. Members of this protein family have highly similar structural and functional characteristics. EGF contains 9 EGF-like domains and 9 LDL-receptor class B repeats. Human EGF is a 6045-Da protein with 53 amino acid residues and three intramolecular disulfide bonds. As a low-molecular-weight polypeptide, EGF was first purified from the mouse submandibular gland, but since then it was found in many human tissues including submandibular gland, parotid gland. It can also be found in human platelets, macrophages, urine, saliva, milk, and plasma. EGF is a growth factor that stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. It results in cellular proliferation, differentiation, and survival. Salivary EGF, which seems also regulated by dietary inorganic iodine, also plays an important physiological role in the maintenance of oro-esophageal and gastric tissue integrity. EGF acts by binding with high affinity to epidermal growth factor receptor on the cell surface and stimulating the intrinsic protein-tyrosine kinase activity of the receptor. The tyrosine kinase activity, in turn, initiates a signal transduction cascade that results in a variety of biochemical changes within the cell - a rise in intracellular calcium levels, increased glycolysis and protein synthesis, and increases in the expression of certain genes including the gene for EGFR - that ultimately lead to DNA synthesis and cell proliferation.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human EGF protein (TMPY-01560)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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