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顶部生物活性储存和溶解信息计算器

Anti-BMP-7 Antibody (7G538)

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产品编号 TMAY-00232

别名 Osteogenic protein 1, OP-1, OP1, Eptotermin alfa, Bone morphogenetic protein 7, BMP7

Anti-BMP-7 Antibody (7G538) 是一种 Mouse 抗体，靶向 BMP-7。Anti-BMP-7 Antibody (7G538) 可用于 ELISA。

Anti-BMP-7 Antibody (7G538)

Anti-BMP-7 Antibody (7G538)

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Rating icon 还可以
产品编号 TMAY-00232 别名 Osteogenic protein 1, OP-1, OP1, Eptotermin alfa, Bone morphogenetic protein 7, BMP7

Anti-BMP-7 Antibody (7G538) 是一种 Mouse 抗体，靶向 BMP-7。Anti-BMP-7 Antibody (7G538) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 1,694
5日内发货
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产品介绍

生物活性
产品描述
Anti-BMP-7 Antibody (7G538) is a Mouse antibody targeting BMP-7. Anti-BMP-7 Antibody (7G538) can be used in ELISA.
别名Osteogenic protein 1, OP-1, OP1, Eptotermin alfa, Bone morphogenetic protein 7, BMP7
Ig Type
Mouse IgG1
克隆号
7G538
交叉反应
Human
特异性
Human BMP7
No cross-reactivity in ELISA with
Human cell lysate (293 cell line)
应用ELISA
推荐剂量
ELISA: 1:1000-1:2000
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human BMP-7 (rh BMP-7; NP_001710.1; Ser 293-His 431). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景BMP-7 (Bone morphogenetic protein 7), also known as osteogenic protein 1 (OP-1), is a bone morphogenetic protein which belongs to the TGF-β superfamily. OP-1 is expressed in the brain, kidneys and bladder. BMP-7 may be involved in bone homeostasis. Osteogenic protein 1 plays a key role in the transformation of mesenchymal cells into bone and cartilage. The phosphorylation of SMAD1 and SMAD5 can be induced by BMP-7, which in turn induce transcription of numerous osteogenic genes. BMP-7 treatment can also induce all of the genetic markers of osteoblast differentiation in many cell types. The expression of BMP-7 causes ventral phenotypes while its complete inhibition creates a dorsal phenotype. Human recombinant BMP-7 protein can be used to aid in the fusion of vertebral bodies to prevent neurologic trauma. It also functions in the treatment of tibial non-union, frequently in cases where a bone graft has failed. It is found that BMP7 has the potential for treatment of chronic kidney disease.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human BMP-7 protein
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

计算器

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关键词

BMP7Protein,Human,Recombinant

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4个月前
5.0
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