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Anti-BMP-7 Antibody (7G538)
还可以产品编号 TMAY-00232
Anti-BMP-7 Antibody (7G538) 是一种 Mouse 抗体，靶向 BMP-7。Anti-BMP-7 Antibody (7G538) 可用于 ELISA。
Anti-BMP-7 Antibody (7G538)
Anti-BMP-7 Antibody (7G538)
还可以产品编号 TMAY-00232
Anti-BMP-7 Antibody (7G538) 是一种 Mouse 抗体，靶向 BMP-7。Anti-BMP-7 Antibody (7G538) 可用于 ELISA。
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产品介绍
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抗原信息
| 产品描述 | Anti-BMP-7 Antibody (7G538) is a Mouse antibody targeting BMP-7. Anti-BMP-7 Antibody (7G538) can be used in ELISA. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 7G538 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:1000-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human BMP-7 (rh BMP-7; NP_001710.1; Ser 293-His 431). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | BMP-7 (Bone morphogenetic protein 7), also known as osteogenic protein 1 (OP-1), is a bone morphogenetic protein which belongs to the TGF-β superfamily. OP-1 is expressed in the brain, kidneys and bladder. BMP-7 may be involved in bone homeostasis. Osteogenic protein 1 plays a key role in the transformation of mesenchymal cells into bone and cartilage. The phosphorylation of SMAD1 and SMAD5 can be induced by BMP-7, which in turn induce transcription of numerous osteogenic genes. BMP-7 treatment can also induce all of the genetic markers of osteoblast differentiation in many cell types. The expression of BMP-7 causes ventral phenotypes while its complete inhibition creates a dorsal phenotype. Human recombinant BMP-7 protein can be used to aid in the fusion of vertebral bodies to prevent neurologic trauma. It also functions in the treatment of tibial non-union, frequently in cases where a bone graft has failed. It is found that BMP7 has the potential for treatment of chronic kidney disease. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human BMP-7 protein |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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