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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-CHD3 Antibody (3C623)

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货号 TMAB-04289

Anti-CHD3 Antibody (3C623) 是一种 Rabbit 抗体，靶向 CHD3。Anti-CHD3 Antibody (3C623) 可用于 IHC-P,IHC-Fr,IF。

Anti-CHD3 Antibody (3C623)

Anti-CHD3 Antibody (3C623)

一键复制产品信息
Rating icon 还可以
货号 TMAB-04289

Anti-CHD3 Antibody (3C623) 是一种 Rabbit 抗体，靶向 CHD3。Anti-CHD3 Antibody (3C623) 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
25 μL
¥ 785
5日内发货
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-CHD3 Antibody (3C623) is a Rabbit antibody targeting CHD3. Anti-CHD3 Antibody (3C623) can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
克隆号
3C623
反应种属
Human,Mouse,Rat
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Nucleus. Cytoplasm > cytoskeleton > centrosome. Associates with centrosomes in interphase and mitosis.
组织特异性Widely expressed.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessiblity to transcription factors by DNA. Conversely, the deacetylation of histones is associated with transcriptional silencing. Chromatin structure alteration may be brought about by the action of ATP-dependent multiprotein complexes. One such complex is the mSin3 corepressor complex, which contains mSin3, the histone deacetylases HDAC1 and HDAC2, the associated proteins SAP 30 and SAP 18, and the autoantigens Mi2-a and Mi2-b.
抗原信息
免疫原
KLH conjugated synthetic peptide: human CHD3
抗原种属
Human
基因名称
CHD3
基因ID
1107
蛋白名称
Chromodomain-helicase-DNA-binding protein 3
Uniprot ID
Q12873
功能
Component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Required for anchoring centrosomal pericentrin in both interphase and mitosis, for spindle organization and centrosome integrity.
化学信息
分子量Theoretical: 226 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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