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顶部生物活性储存和溶解信息计算器

Anti-ITGA5 Antibody (3X608)

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产品编号 TMAH-00643

别名 VLA-5, ITGA5, Integrin α-F, Integrin α-5, Integrin Alpha-F, Integrin Alpha-5, FNRA, Fibronectin Receptor Subunit α, Fibronectin Receptor Subunit Alpha, CD49e, CD49 Antigen-Like Family Member E

Anti-ITGA5 Antibody (3X608) 是一种抗体，靶向 ITGA5。Anti-ITGA5 Antibody (3X608) 可用于 ELISA,IHC。

Anti-ITGA5 Antibody (3X608)

Anti-ITGA5 Antibody (3X608)

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Rating icon 还可以
产品编号 TMAH-00643 别名 VLA-5, ITGA5, Integrin α-F, Integrin α-5, Integrin Alpha-F, Integrin Alpha-5, FNRA, Fibronectin Receptor Subunit α, Fibronectin Receptor Subunit Alpha, CD49e, CD49 Antigen-Like Family Member E

Anti-ITGA5 Antibody (3X608) 是一种抗体，靶向 ITGA5。Anti-ITGA5 Antibody (3X608) 可用于 ELISA,IHC。

规格价格库存数量
50 μL
¥ 1,305
5日内发货
100 μL
¥ 2,190
5日内发货
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产品介绍

生物活性
产品描述
Anti-ITGA5 Antibody (3X608) is an antibody targeting ITGA5. Anti-ITGA5 Antibody (3X608) can be used in ELISA,IHC.
别名VLA-5, ITGA5, Integrin α-F, Integrin α-5, Integrin Alpha-F, Integrin Alpha-5, FNRA, Fibronectin Receptor Subunit α, Fibronectin Receptor Subunit Alpha, CD49e, CD49 Antigen-Like Family Member E
Ig Type
hIgG1
克隆号
3X608
交叉反应
Human
验证活性
IHC image of TMAH-00643 diluted at 1:50 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-human polymer IgG labeled by HRP and visualized using 0.05% DAB.
应用ELISAIHC
推荐剂量
IHC:1:50-1:200.
抗体种类
Monoclonal
亚细胞定位Membrane; Single-pass type I membrane protein. Cell junction, focal adhesion. Cell surface.
构建方式Recombinant Antibody
纯化方式Affinity-chromatography
性状Liquid
缓冲液Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4.
研究背景Integrin alpha-5/beta-1 (ITGA5:ITGB1) is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. ITGA5:ITGB1 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1. ITGA5:ITGB1 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1. ITGA5:ITGB1 is a receptor for IL1B and binding is essential for IL1B signaling. ITGA5:ITGB3 is a receptor for soluble CD40LG and is required for CD40/CD40LG signaling. (Microbial infection) Integrin ITGA5:ITGB1 acts as a receptor for Human metapneumovirus. (Microbial infection) Integrin ITGA2:ITGB1 acts as a receptor for Human parvovirus B19. (Microbial infection) In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human ITGA5 Protein
抗原种属
Human
基因名称
ITGA5
基因ID
3678
Uniprot ID
P08648
研究领域
Signal transduction, Stem cells
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

VLA5VLA 5ITGA-5ITGA 5Integrin a-FIntegrin a-5

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