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顶部生物活性储存和溶解信息计算器

Anti-Phospho-ROCK2 (Tyr722) Polyclonal Antibody

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Anti-Phospho-ROCK2 (Tyr722) Polyclonal Antibody
产品编号 TMAC-03617
别名 ROCK2 (p-Y722), ROCK2 (p-Tyr722), p-ROCK2 (Y722), p-ROCK2 (Tyr722)

Anti-Phospho-ROCK2 (Tyr722) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-ROCK2 (Tyr722)。Anti-Phospho-ROCK2 (Tyr722) Polyclonal Antibody 可用于 WB。

Anti-Phospho-ROCK2 (Tyr722) Polyclonal Antibody

Anti-Phospho-ROCK2 (Tyr722) Polyclonal Antibody

Rating icon 还可以
Anti-Phospho-ROCK2 (Tyr722) Polyclonal Antibody
产品编号 TMAC-03617 别名 ROCK2 (p-Y722), ROCK2 (p-Tyr722), p-ROCK2 (Y722), p-ROCK2 (Tyr722)

Anti-Phospho-ROCK2 (Tyr722) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-ROCK2 (Tyr722)。Anti-Phospho-ROCK2 (Tyr722) Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,480
5日内发货
100 μL
¥ 2,245
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-ROCK2 (Tyr722) Polyclonal Antibody is a Rabbit antibody targeting Phospho-ROCK2 (Tyr722). Anti-Phospho-ROCK2 (Tyr722) Polyclonal Antibody can be used in WB.
别名ROCK2 (p-Y722), ROCK2 (p-Tyr722), p-ROCK2 (Y722), p-ROCK2 (Tyr722)
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of extracts from Rat kindey using ROCK2 (Phospho-Tyr722) antibody TMAC-03617. The lane on the left is treated with the antigen-specific peptide.
2. Western Blot analysis of lysates of mouse spleen, using primary antibody at 1:1000 dilution.
应用
WB
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Polyclonal Antibody
纯化方式Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
性状Liquid
缓冲液Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of ADD1, BRCA2, CNN1, EZR, DPYSL2, EP300, MSN, MYL9/MLC2, NPM1, RDX, PPP1R12A and VIM. Phosphorylates SORL1 and IRF4. Acts as a negative regulator of VEGF-induced angiogenic endothelial cell activation. Positively regulates the activation of p42/MAPK1-p44/MAPK3 and of p90RSK/RPS6KA1 during myogenic differentiation. Plays an important role in the timely initiation of centrosome duplication. Inhibits keratinocyte terminal differentiation. May regulate closure of the eyelids and ventral body wall through organization of actomyosin bundles. Plays a critical role in the regulation of spine and synaptic properties in the hippocampus.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
Peptide sequence around phosphorylation site of Tyrosine 722 (K-I-Y(p)-E-S) derived from Human ROCK2
抗原种属
human
Uniprot ID
O75116
化学信息
分子量Actual: 160 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

ROCK2 (pY722)ROCK2 (pTyr722)ROCK2 (phospho-Y722)ROCK2 (phospho-Tyr722)pROCK2 (Y722)pROCK2 (Tyr722)

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4个月前
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