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别名 肿瘤坏死因子, TNFSF1, TNFB, TNF β, lymphotoxin α, lymphotoxin alpha, LT
Anti-TNF beta Antibody-HRP (7E588) 是一种 HRP-conjugated Rabbit 抗体,靶向 TNF beta。Anti-TNF beta Antibody-HRP (7E588) 可用于 ELISA。
Anti-TNF beta Antibody-HRP (7E588) 是一种 HRP-conjugated Rabbit 抗体,靶向 TNF beta。Anti-TNF beta Antibody-HRP (7E588) 可用于 ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μg | ¥ 3,495 | 5日内发货 |
| 产品描述 | Anti-TNF beta Antibody-HRP (7E588) is a HRP-conjugated Rabbit antibody targeting TNF beta. Anti-TNF beta Antibody-HRP (7E588) can be used in ELISA. |
| 别名 | 肿瘤坏死因子, TNFSF1, TNFB, TNF β, lymphotoxin α, lymphotoxin alpha, LT |
| Ig Type | Rabbit IgG |
| 克隆号 | 7E588 |
| 交叉反应 | Human |
| 特异性 | Human Lymphotoxin alpha/TNF beta |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 0.1-1 μg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human TNF-beta / TNFSF1 / Lymphotoxin alpha (rh TNF-beta / TNFSF1 / Lymphotoxin alpha ; TMPY-02153; P01374; Leu35-Leu205), and conjugated with horseradish-peroxidase (HRP). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Lymphotoxin-alpha, also known as LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1, LTA TNFSF1, and TNFB, is a secreted protein that belongs to the tumor necrosis factor family. TNF-beta/TNFSF1/Lymphotoxin alpha is highly inducible, secreted, and exists as a homotrimeric molecule. It is a cytokine that in its homotrimeric form binds to TNFRSF1A / TNFR1, TNFRSF1B / TNFBR, and TNFRSF14 / HVEM. In its heterotrimeric form with LTB, TNF-beta/TNFSF1/Lymphotoxin alpha binds to TNFRSF3 / LTBR. Lymphotoxin is produced by lymphocytes and cytotoxic for a wide range of tumor cells. TNF-beta/TNFSF1/Lymphotoxin alpha forms heterotrimers with lymphotoxin-beta which anchors lymphotoxin-alpha to the cell surface. It mediates a large variety of inflammatory, immunostimulatory, and antiviral responses. TNF-beta/TNFSF1/Lymphotoxin alpha is also involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in TNF-beta/TNFSF1/Lymphotoxin alpha are a cause of susceptibility psoriatic arthritis which is an inflammatory, seronegative arthritis associated with psoriasis. It is a heterogeneous disorder ranging from a mild, non-destructive disease to a severe, progressive, erosive arthropathy. |
| 偶联 | HRP |
| 其他可选修饰符 | Unconjugated |
| 可提供抗体种类 | 2 |
| 免疫原 | Recombinant Protein: Human TNF-beta / TNFSF1 / Lymphotoxin alpha protein (TMPY-02153) |
| 抗原种属 | Human |
| 研究领域 | Neuroinflammation |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. Keep away from direct sunlight. |
| 运输方式 | Shipping with blue ice. |
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