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Anti-Kallikrein 3/KLK3 Antibody (6R985)

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Anti-Kallikrein 3/KLK3 Antibody (6R985)
产品编号 TMAB-01012
别名 PSA, KLK2A1, kallikrein related peptidase 3, Hk3, APS

Anti-Kallikrein 3/KLK3 Antibody (6R985) 是一种 Mouse 抗体，靶向 Kallikrein 3/KLK3。Anti-Kallikrein 3/KLK3 Antibody (6R985) 可用于 WB,IHC-P,IHC-Fr,IF,ELISA。

Anti-Kallikrein 3/KLK3 Antibody (6R985)

Anti-Kallikrein 3/KLK3 Antibody (6R985)

Rating icon 还可以
Anti-Kallikrein 3/KLK3 Antibody (6R985)
产品编号 TMAB-01012 别名 PSA, KLK2A1, kallikrein related peptidase 3, Hk3, APS

Anti-Kallikrein 3/KLK3 Antibody (6R985) 是一种 Mouse 抗体，靶向 Kallikrein 3/KLK3。Anti-Kallikrein 3/KLK3 Antibody (6R985) 可用于 WB,IHC-P,IHC-Fr,IF,ELISA。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,960
5日内发货
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产品介绍

生物活性
产品描述
Anti-Kallikrein 3/KLK3 Antibody (6R985) is a Mouse antibody targeting Kallikrein 3/KLK3. Anti-Kallikrein 3/KLK3 Antibody (6R985) can be used in WB,IHC-P,IHC-Fr,IF,ELISA.
别名PSA, KLK2A1, kallikrein related peptidase 3, Hk3, APS
Ig Type
IgG
克隆号
6R985
交叉反应
Human
验证活性
Tissue/cell: human prostate carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min;
Incubation: Anti-PSa (PA5) Polyclonal Antibody, Unconjugated (TMAB-01012) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining.
应用
WB
IHC-P
IHC-Fr
IF
ELISA
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Secreted.
组织特异性Prostate.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M PBS (pH7.4) with 0.02% Proclin300.
浓度1 mg/mL
研究背景Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
抗原信息
免疫原
Full length native protein purified from human
抗原种属
Human
基因名称
KLK3
基因ID
354
蛋白名称
Prostate-specific antigen
Uniprot ID
P07288
研究领域
Tumor antigens,Tumor-associated antigens,Proteases,Kallikreins,Tumor Associated
功能
Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum.
化学信息
分子量Theoretical: 23 kDa. Actual: 29/35 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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