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Anti-MICB Antibody (2D186)
还可以产品编号 TMAY-01132
Anti-MICB Antibody (2D186) 是一种 Rabbit 抗体，靶向 MICB。Anti-MICB Antibody (2D186) 可用于 WB。
Anti-MICB Antibody (2D186)
Anti-MICB Antibody (2D186)
还可以产品编号 TMAY-01132
Anti-MICB Antibody (2D186) 是一种 Rabbit 抗体，靶向 MICB。Anti-MICB Antibody (2D186) 可用于 WB。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-MICB Antibody (2D186) is a Rabbit antibody targeting MICB. Anti-MICB Antibody (2D186) can be used in WB. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 2D186 |
| 交叉反应 | Human |
| 验证活性 | Anti-MICB rabbit monoclonal antibody at 1:500 dilution. -Lane A: U87MG Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution. -Developed using the Odyssey technique. -Performed under reducing conditions. -Predicted band size:40 kDa. -Observed band size:67 kDa |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-1:1000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human MICB (rh MICB ; TMPY-01066; NP_005922.2; Met1-Gly298). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | MHC class I polypeptide-related sequence B, also known as MICB, is a heavily glycosylated protein serving as a ligand for the type II receptor NKG2D. MICB shares 85% amino acid identity with MICA, a closely related protein, both of which contain three extracellular immunoglobulin-like domains, but without the capacity to bind peptide or interact with beta-2-microglobulin. acting as a stress-induced self-antigen, binding of MICB to the NKG2D receptor activates the cytolytic response of natural killer (NK) cells, CD8+αβ T cells, and γδ T cells on which the receptor is expressed. MICA/B is minimally expressed on normal cells, but are frequently expressed on epithelial tumors and can be induced by bacterial and viral infections. MICA/B recognition thus is involved in tumor surveillance, viral infections, and autoimmune diseases. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human MICB protein (TMPY-01066) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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